Evidence map›Paper›PMID 33763465›Full record

ArticleFrontiers in veterinary science2021

Differential Signals From TNFα-Treated and Untreated Embryos in Uterine Tissues and Splenic CD4

Katarzyna Buska-Mach, Anna Ewa Kedzierska, Adam Lepczynski, Agnieszka Herosimczyk, Małgorzata Ozgo, Pawel Karpinski, Agnieszka Gomulkiewicz, Daria Lorek, Anna Slawek, Piotr Dziegiel and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Katarzyna Buska-MachHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.
Anna Ewa KedzierskaHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.
Adam LepczynskiDepartment of Physiology, Cytobiology and Proteomics, West Pomeranian University of Technology, Szczecin, Poland.
Agnieszka HerosimczykDepartment of Physiology, Cytobiology and Proteomics, West Pomeranian University of Technology, Szczecin, Poland.
Małgorzata OzgoDepartment of Physiology, Cytobiology and Proteomics, West Pomeranian University of Technology, Szczecin, Poland.
Pawel KarpinskiHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.
Agnieszka GomulkiewiczDepartment of Human Morphology and Embryology, Wroclaw Medical University, Wrocław, Poland.
Daria LorekHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.
Anna SlawekHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.
Piotr DziegielDepartment of Human Morphology and Embryology, Wroclaw Medical University, Wrocław, Poland.
Anna Chelmonska-SoytaHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.
Ludwik Hirszfeld Institute of Immunology and Experimental Therapy · PLWest Pomeranian University of Technology · PLWroclaw Medical University · PLPolish Academy of Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main aim of this study was to examine if a female mouse body in preimplantation pregnancy can distinguish between embryos of normal and impaired biological quality in the local and peripheral compartments. Normal (control group) and TNFα (tumor necrosis factor-α)-treated embryos (experimental group) at the morula stage were non-surgically transferred into the uteri of CD-1 strain [Crl:CD1(Icr)] female murine recipients. Twenty-four hours after the embryo transfer, females were euthanised, and uteri and spleens were dissected. In uterine tissues (local compartment), we assessed the expression of 84 genes comprising nine signal transduction pathways, using a modified RT

Indexed as

CD4 lymphocytesembryopregnancypreimplantationproteomeT cellsTNFuterus

Identifiers

PMID33763465
PMCPMC7982469
OpenAlexW3134687146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.