Evidence map›Paper›PMID 33763246›Full record

ArticleArab journal of urology2020

Comparing oncological outcomes of laparoscopic vs open radical nephroureterectomy for the treatment of upper tract urothelial carcinoma: A propensity score-matched analysis.

Marco Moschini, Stefania Zamboni, Luca Afferi, Benjamin Pradere, Mohammad Abufaraj, Francesco Soria, David D'Andrea, Morgan Roupret, Alexandre De la Taille, Claudio Simeone and 18 more

Open access · diamondAbstract read
In one paragraph

Article in Arab journal of urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 17 institutions in 11 countries.

Marco MoschiniDepartment of Urology, Vienna General Hospital, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0002-3084-2458
Stefania ZamboniUrology Unit, ASST Spedali Civili, Brescia, Italy.
Luca AfferiDepartment of Urology, Luzerner Kantonsspital, Luzern, Switzerland.
Benjamin PradereDepartment of Urology, Vienna General Hospital, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0002-7768-8558
Mohammad AbufarajDepartment of Urology, Vienna General Hospital, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0002-6603-6319
Francesco SoriaDepartment of Urology, Vienna General Hospital, Medical University of Vienna, Vienna, Austria.
David D'AndreaDepartment of Urology, Vienna General Hospital, Medical University of Vienna, Vienna, Austria.
Morgan RoupretUrology, Assistance Publique-Hôpitaux De Paris (AP-HP), Sorbonne University, Hopital Pitié Salpétrière, Paris, France.
Alexandre De la TailleDepartment of Urology, Assistance Publique-Hôpitaux De Paris (AP-HP) CHU Mondor, Faculté De Médecine, Henri Mondor Hospital, Créteil, France.
Claudio SimeoneUrology Unit, ASST Spedali Civili, Brescia, Italy.
Agostino MatteiDepartment of Urology, Luzerner Kantonsspital, Luzern, Switzerland.
Romain MathieuUrology, Rennes University Hospital (France), Rennes, France.
Karim BensalahUrology, Rennes University Hospital (France), Rennes, France.
Manfred Peter WirthDepartment of Urology, University Hospital Carl Gustav Carus, Dresden, Germany.
Francesco MontorsiDepartment of Urology, Urological Research Institute, Vita-Salute University, San Raffaele Scientific Institute, Milan, Italy.
Alberto BrigantiDepartment of Urology, Urological Research Institute, Vita-Salute University, San Raffaele Scientific Institute, Milan, Italy.
Andrea GallinaDepartment of Urology, Urological Research Institute, Vita-Salute University, San Raffaele Scientific Institute, Milan, Italy.
Giuseppe SimoneDepartment of Urology, 'Regina Elena' National Cancer Institute, Rome, Italy.
Michele GallucciDepartment of Urology, 'Regina Elena' National Cancer Institute, Rome, Italy.
Carlo Di BonaDepartment of Urology, Luzerner Kantonsspital, Luzern, Switzerland.
Giancarlo MarraDivision of Urology, Department of Surgical Sciences, University of Studies of Torino, Turin, Italy.
Andrea MariDepartment of Urology, University of Florence, Unit of Oncologic Minimally Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.
Ettore Di TrapaniDepartment of Urology, European Institute of Oncology (IEO), Milan, Italy.
Mario Alvarez MaestroDepartment of Urology, La Paz University Hospital, Madrid, Spain.
Wojciech KrajewskiDepartment of Urology and Oncologic Urology, Wrocław Medical University, Wroclaw, Poland.
Shahrokh F ShariatDepartment of Urology, Vienna General Hospital, Medical University of Vienna, Vienna, Austria.
Evanguelos XylinasDepartment of Urology, CHU Bichat, Paris, France.
Philipp BaumeisterDepartment of Urology, Luzerner Kantonsspital, Luzern, Switzerland.
Luzerner Kantonsspital · CHVienna General Hospital · ATVita-Salute San Raffaele University · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITCentre Hospitalier Universitaire de Rennes · FRAssistance Publique – Hôpitaux de Paris · FRAzienda Ospedaliero-Universitaria Careggi · ITEuropean Institute of Oncology · ITHôpital Bichat-Claude-Bernard · FRHospital Universitario La Paz · ESSechenov University · RUSorbonne Université · FRUniversité de Tours · FRUniversity Hospital Carl Gustav Carus · DEUniversity of Jordan · JOUniversity of Turin · ITWroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare oncological outcomes of open (ORNU) and laparoscopic radical nephroureterectomy (LRNU) after controlling for preoperative patient-derived factors. PATIENTS AND

methodsWe evaluated a multi-institutional collaborative database composed of 3984 patients diagnosed with upper tract urothelial carcinoma (UTUC) treated with RNU between 2006 and 2018. To adjust for potential selection bias, propensity score matching adjusted for age, gender and American society Anesthesiology (ASA) score was performed with one ORNU patient matched to one LRNU patient. Uni- and multivariable Cox regression evaluating the risk of overall recurrence, cancer-specific mortality (CSM) and overall mortality (OM) in the overall population and after propensity matching were performed.

resultsIn total, 3984 patients underwent RNU, of these 3227 (81%) patients were treated with ORNU and 757 (19%) patients with LRNU. Within a median follow-up of 62 months, 1276 recurrences, 844 CSMs and 1128 OMs were recorded. On multivariable analyses, the LRNU approach was associated with an increased risk of overall recurrence (hazard ratio [HR] 1.26, 95% confidence interval [CI] 1.03-1.54;

conclusionOur present data suggest that even if the type of approach to RNU was associated with different survival outcomes considering the overall population, this difference vanished when adjusted for potential confounders in propensity matching analyses. Therefore, we found that LRNU is not inferior to the ORNU approach for the treatment of UTUC. ABBREVIATIONS: ASA: American Society of Anesthesiology; CIS: carcinoma

Indexed as

laparoscopicopenradical nephroureterectomyRNUUpper tract urothelial carcinomaUTUC

Identifiers

PMID33763246
PMCPMC7954493
OpenAlexW3083482555

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.