Evidence map›Paper›PMID 33763231›Full record

ArticleConservation physiology2021

Amphibian reproductive technologies: approaches and welfare considerations.

Aimee J Silla, Natalie E Calatayud, Vance L Trudeau

Abstract read
In one paragraph

Article in Conservation physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Seasonal dynamic and individual determinants ofInternational journal for parasitology. Parasites and wildlife · 2026
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  5. Biobanking biodiversity: recent strategies, challenges, and opportunities.The Journal of reproduction and development · 2026
    Review
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  7. Article
  8. Review
  9. Article
  10. Article
  11. Reproduction in the frogAnimal reproduction · 2025
    Article
  12. Ameliorative effects of vitamin C and garlic (Frontiers in veterinary science · 2025
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aimee J SillaSchool of Earth, Atmospheric and Life Sciences, University of Wollongong, Northfields Ave, Wollongong, New South Wales 2522, Australia.
Natalie E CalatayudTaronga Institute of Science and Learning, Taronga Conservation Society Australia, Taronga, Western Plains Zoo, Obley Rd, Dubbo, New South Wales 2830, Australia.
Vance L TrudeauDepartment of Biology, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Captive breeding and reintroduction programs have been established for several threatened amphibian species globally, but with varied success. This reflects our relatively poor understanding of the hormonal control of amphibian reproduction and the stimuli required to initiate and complete reproductive events. While the amphibian hypothalamo-pituitary-gonadal (HPG) axis shares fundamental similarities with both teleosts and tetrapods, there are more species differences than previously assumed. As a result, many amphibian captive breeding programs fail to reliably initiate breeding behaviour, achieve high rates of fertilization or generate large numbers of healthy, genetically diverse offspring. Reproductive technologies have the potential to overcome these challenges but should be used in concert with traditional methods that manipulate environmental conditions (including temperature, nutrition and social environment). Species-dependent methods for handling, restraint and hormone administration (including route and frequency) are discussed to ensure optimal welfare of captive breeding stock. We summarize advances in hormone therapies and discuss two case studies that illustrate some of the challenges and successes with amphibian reproductive technologies: the mountain yellow-legged frog (

Indexed as

Assisted reproductive technologiescaptive breedingendocrinologygenetic managementreproductionspawning

Identifiers

PMID33763231
PMCPMC7976225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.