Evidence map›Paper›PMID 33763205›Full record

ArticleF1000Research2020

VIRdb 2.0: Interactive analysis of comorbidity conditions associated with vitiligo pathogenesis using co-expression network-based approach.

Priyansh Srivastava, Mehak Talwar, Aishwarya Yadav, Alakto Choudhary, Sabyasachi Mohanty, Samuel Bharti, Priyanka Narad, Abhishek Sengupta

Open access · goldAbstract read
In one paragraph

Article in F1000Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Vitiligo Information Resource database v3.NPJ systems biology and applications · 2026
    Article
  2. Article
  3. Multi-Omics Research Strategies for Psoriasis and Atopic Dermatitis.International journal of molecular sciences · 2023
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Priyansh SrivastavaAmity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, 201301, India.ORCID 0000-0003-2618-5296
Mehak TalwarAmity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, 201301, India.
Aishwarya YadavAmity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, 201301, India.
Alakto ChoudharyAmity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, 201301, India.
Sabyasachi MohantyAmity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, 201301, India.ORCID 0000-0001-7099-5750
Samuel BhartiAmity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, 201301, India.ORCID 0000-0003-4190-7058
Priyanka NaradAmity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, 201301, India.ORCID 0000-0001-7317-654X
Abhishek SenguptaAmity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, 201301, India.ORCID 0000-0002-3958-3675
Amity University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitiligo is a disease of mysterious origins in the context of its occurrence and pathogenesis. The autoinflammatory theory is perhaps the most widely accepted theory that discusses the occurrence of Vitiligo. The theory elaborates the clinical association of vitiligo with autoimmune disorders such as Psoriasis, Multiple Sclerosis and Rheumatoid Arthritis and Diabetes. In the present work, we discuss the comprehensive set of differentially co-expressed genes involved in the crosstalk events between Vitiligo and associated autoimmune disorders (Psoriasis, Multiple Sclerosis and Rheumatoid Arthritis). We progress our previous tool, Vitiligo Information Resource (VIRdb), and incorporate into it a compendium of Vitiligo-related multi-omics datasets and present it as VIRdb 2.0. It is available as a web-resource consisting of statistically sound and manually curated information. VIRdb 2.0 is an integrative database as its datasets are connected to KEGG, STRING, GeneCards, SwissProt, NPASS. Through the present study, we communicate the major updates and expansions in the VIRdb and deliver the new version as VIRdb 2.0. VIRdb 2.0 offers the maximum user interactivity along with ease of navigation. We envision that VIRdb 2.0 will be pertinent for the researchers and clinicians engaged in drug development for vitiligo.

Indexed as

Arthritis, RheumatoidAutoimmune DiseasesPsoriasisVitiligoComorbidityHumansco-expressed GenesComorbidity NetworkDatabaseDifferential GenesVitiligo

Identifiers

PMID33763205
PMCPMC7953917
OpenAlexW3080960075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.