Evidence map›Paper›PMID 33763032›Full record

ArticleFrontiers in endocrinology2021

Serum Lipid Levels and Treatment Outcomes in Women Undergoing Assisted Reproduction: A Retrospective Cohort Study.

Wang-Yu Cai, Xi Luo, Erxidi Chen, Houyi Lv, Kaiyou Fu, Xiao-Ke Wu, Jian Xu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Wang-Yu CaiFourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China.
Xi LuoDepartment of Gynecology, Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Erxidi ChenWomen's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Houyi LvWomen's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Kaiyou FuWomen's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xiao-Ke WuDepartment of Obstetrics and Gynecology, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, China.
Jian XuFourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China.
Women's Hospital, School of Medicine, Zhejiang University · CNAnhui Medical University · CNFirst Affiliated Hospital of Heilongjiang University of Chinese Medicine · CNZhejiang Chinese Medical University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate associations between serum lipid levels and treatment outcomes in women undergoing assisted reproduction. Materials and Methods: The study included 2011 women who underwent Results: Higher HDL-C quartiles were associated with more oocytes retrieved. Lower TC (quartile 1 odds ratio [OR] 1.59 [1.21-2.08], quartile 3 OR 1.36 [1.04-1.77]), LDL-C (quartile 1 OR 1.41 [1.07-1.86]), and TG (quartile 2 OR 1.39 [1.06-1.84]) were independently associated with clinical pregnancy after adjusting for potential confounders. Lower LDL-C (quartile 1 OR 2.22 [1.58-3.13], quartile 2 OR 1.78 [1.27-2.50], quartile 3 OR 1.51 [1.07-2.13]), TC (quartile 1 OR 1.39 [1.00-1.93]), TG (quartile 1 OR 1.44 [1.03-2.03], quartile 2 OR 1.46 [1.04-2.04], quartile 3 OR 1.44 [1.04-1.99]), and higher HDL-C (quartile 2 OR 0.71 [0.51-0.99]) were independently associated with live birth. Higher LDL-C (quartile 1 OR 0.44 [0.30-0.66], quartile 2 OR 0.49 [0.33-0.73], quartile 3 OR 0.63 [0.43-0.94]) and lower HDL-C (quartile 1 OR 1.60 [1.07-2.39]) were independently associated with miscarriage. Conclusions: Serum lipid levels were associated with treatment outcomes in women undergoing assisted reproduction.

Indexed as

Reproductive Techniques, AssistedAbortion, SpontaneousAdolescentAdultCholesterol, HDLCholesterol, LDLFemaleFertilization in VitroHumansInfertility, FemaleLipidsLive BirthMiddle AgedPregnancyPregnancy OutcomeRetrospective StudiesCholesterol, HDLCholesterol, LDLLipidsTriglyceridesassisted reproductionlipidlive birthmiscarriagepregnancyreproduction

Identifiers

PMID33763032
PMCPMC7982671
OpenAlexW3134892632

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.