Evidence map›Paper›PMID 33762902›Full record

ArticleFrontiers in neuroscience2021

Adrenergic Mechanisms of Audiogenic Seizure-Induced Death in a Mouse Model of

Eric R Wengert, Ian C Wenker, Elizabeth L Wagner, Pravin K Wagley, Ronald P Gaykema, Jung-Bum Shin, Manoj K Patel

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  12. Seizures Cause Prolonged Impairment of Ventilation, COThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Somatostatin-Positive Interneurons Contribute to Seizures inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Eric R WengertDepartment of Anesthesiology, University of Virginia Health System, Charlottesville, VA, United States.
Ian C WenkerDepartment of Anesthesiology, University of Virginia Health System, Charlottesville, VA, United States.
Elizabeth L WagnerDepartment of Neuroscience, University of Virginia School of Medicine, Charlottesville, VA, United States.
Pravin K WagleyDepartment of Anesthesiology, University of Virginia Health System, Charlottesville, VA, United States.
Ronald P GaykemaDepartment of Anesthesiology, University of Virginia Health System, Charlottesville, VA, United States.
Jung-Bum ShinNeuroscience Graduate Program, University of Virginia Health System, Charlottesville, VA, United States.
Manoj K PatelDepartment of Anesthesiology, University of Virginia Health System, Charlottesville, VA, United States.
University of Virginia Health System · USUniversity of Virginia · US

Funding

Significance of Myo7a isoforms in hair cell functionR01DC018842 · NIDCD · UNIVERSITY OF VIRGINIA · PI Jung-Bum Shin · 2020 to 2026
$2.9M
Training in Cell and Molecular BiologyT32GM139787 · NIGMS · UNIVERSITY OF VIRGINIA · PI Bryce Paschal · 2021 to 2026
$2.5M
Pathogenesis of epilepsy in a SCN8A human mutation mouse modelR01NS103090 · NINDS · UNIVERSITY OF VIRGINIA · PI PATEL, MANOJ K · 2018 to 2022
$1.8M
Role of XIRP2 in hair cell function and degenerationR01DC014254 · NIDCD · UNIVERSITY OF VIRGINIA · PI SHIN, JUNG-BUM · 2015 to 2019
$1.7M
Mechanisms Mediating Repair of Stereocilia F-actin in Sensory Hair CellsF31DC017370 · NIDCD · UNIVERSITY OF VIRGINIA · PI WAGNER, ELIZABETH LEE · 2018 to 2021
$109k
Depolarization block of inhibitory neurons impacts neuronal function in epileptic encephalopathyF31NS115451 · NINDS · UNIVERSITY OF VIRGINIA · PI WENGERT, ERIC RYAN · 2019 to 2020
$61k
NIDCD NIH HHS F31 DC017370NIDCD NIH HHS R01 DC014254NIDCD NIH HHS R01 DC018842NIGMS NIH HHS T32 GM139787NINDS NIH HHS F31 NS115451NINDS NIH HHS R01 NS103090
6 · The paper itself

Abstract

Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death amongst patients whose seizures are not adequately controlled by current therapies. Patients with

Indexed as

adrenergic receptorsaudiogenic seizuresrespiratory arrestSCN8A encephalopathySUDEP

Identifiers

PMID33762902
PMCPMC7982890
OpenAlexW3135580924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.