ReviewNeuro-ophthalmology (Aeolus Press)2021
Diagnosing Optic Disc Drusen in the Modern Imaging Era: A Practical Approach.
Review in Neuro-ophthalmology (Aeolus Press), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 38 citations in OpenAlex.
- Risk stratification of visual field progression in optic disc drusen with and without glaucoma.International ophthalmology · 2026Article
- Diagnostic Role of Multimodal Imaging in Optic Disc Diseases.Diagnostics (Basel, Switzerland) · 2026Review
- Multimodal OCT/OCT-A Risk Stratification in Optic Disc Drusen: Drusen Height, Peripapillary Perfusion, and Visual Field Slope Identify Fast Progressors.Diagnostics (Basel, Switzerland) · 2026Article
- Optic Disc Flavoprotein Fluorescence Imaging as a Novel Method to Quantify Disease Burden in Optic Disc Drusen.American journal of ophthalmology · 2026Article
- A Systematic Review of Optic Disc Drusen in the Modern Imaging Era: Structure-Function Correlates, Diagnostic Performance, and NAION Co-Occurrence.Diagnostics (Basel, Switzerland) · 2025Review
- Identifying biomarkers for papilledema and pseudopapilledema.Scientific reports · 2025Article
- Prevalence Screening for Familial Optic Disc Drusen: A Cross-Sectional Study.Neuro-ophthalmology (Aeolus Press) · 2025Article
- Effect of Intraocular Pressure Lowering Treatment on Peripapillary and Macular Vessel Density on Normotensive Eyes with Optic Disc Drusen: A Randomized Controlled Trial.Neuro-ophthalmology (Aeolus Press) · 2025Article
- Dual U-Net with multi-task attention for automated eyelid curvature quantification.Frontiers in medicine · 2025Article
- Imaging the optic nerve with optical coherence tomography.Eye (London, England) · 2024Review
- Advantages and Pitfalls of the Use of Optical Coherence Tomography for Papilledema.Current neurology and neuroscience reports · 2024Review
- Diagnosis of Optic Disc Oedema: Fundus Features, Ocular Imaging Findings, and Artificial Intelligence.Neuro-ophthalmology (Aeolus Press) · 2023Review
- Peripapillary hyper-reflective ovoid mass-like structures (PHOMS): clinical significance, associations, and prognostic implications in ophthalmic conditions.Frontiers in neurology · 2023Review
- Comparison of Spectral-Domain OCT versus Swept-Source OCT for the Detection of Deep Optic Disc Drusen.Diagnostics (Basel, Switzerland) · 2022Article
- The Effects of Visual Field Loss from Optic Disc Drusen on Performance in a Driving Simulator.Neuro-ophthalmology (Aeolus Press) · 2022Article
- Peripapillary Hyper-reflective Ovoid Mass-like Structure (PHOMS): An Optical Coherence Tomography Marker of Axoplasmic Stasis in the Optic Nerve Head.Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society · 2021Article
- Multimodal Imaging Features of Optic Disc Drusen.American journal of ophthalmology · 2021Article
- Optic disc drusen: Recent developments on a slow-moving condition.Taiwan journal of ophthalmologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Optic disc drusen (ODD) are a well-recognised cause of an elevated optic disc appearance. When visible with ophthalmoscopy and fundus photography, ODD are readily identified. Yet, in more subtle cases of ODD, ancillary testing may be needed to render the diagnosis. Facilitating the diagnosis of ODD has clinical relevance, because affected individuals may otherwise undergo unnecessary costly and invasive investigations to rule out raised intracranial pressure and other causes of optic disc oedema. In this review, the role of established and emerging optical coherence tomography (OCT) techniques in the diagnosis and management of ODD cases is reviewed. A practical approach is taken to explain how to optimise use of commercially available OCT technology in the clinical setting. Optical coherence tomography provides many advantages over other imaging modalities in the diagnosis of ODD, including the ability to correlate retinal measures of neuroaxonal structure with drusen characteristics. Earlier spectral domain OCT techniques, however, were hindered by poor penetrance. In the modern imaging era, enhanced depth imaging OCT and swept source OCT enable higher resolution of ODD and other optic nerve head structures that might otherwise be mistaken for drusen. Ongoing studies featuring OCT angiography indicate that this technique may provide complementary information about microvascular supply that correlate with structural measures of optic nerve injury. Advances in OCT will continue to improve diagnostic accuracy and inform clinical understanding regarding structure-function correlations germane to the longitudinal follow up of ODD patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.