ArticleScientific reports2021
Effects of Lactobacillus salivarius isolated from feces of fast-growing pigs on intestinal microbiota and morphology of suckling piglets.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 34 citations in OpenAlex.
- The Role of ProbioticsInternational journal of molecular sciences · 2026Review
- Dietary supplementation ofJournal of animal science and technology · 2025Article
- Dietary bile acid supplementation improves the intestinal health and growth performance of piglets partially through the FXR/AQPs pathway.Porcine health management · 2025Article
- Impact ofMicroorganisms · 2024Article
- UnderstandingFoods (Basel, Switzerland) · 2024Review
- Article
- Anti-Bordetella bronchiseptica effects of targeted bacteriophages via microbiome and metabolic mediated mechanisms.Scientific reports · 2023Article
- The Effect of Maternal Probiotic or Synbiotic Supplementation on Sow and Offspring Gastrointestinal Microbiota, Health, and Performance.Animals : an open access journal from MDPI · 2023Review
- Probiotics and Postbiotics as an Alternative to Antibiotics: An Emphasis on Pigs.Pathogens (Basel, Switzerland) · 2023Review
- The Influence ofAnimals : an open access journal from MDPI · 2023Article
- Effects of dietary supplementation of bacteriophage cocktail on health status of weanling pigs in a non-sanitary environment.Journal of animal science and biotechnology · 2023Article
- Biological Functions of Exopolysaccharides from Lactic Acid Bacteria and Their Potential Benefits for Humans and Farmed Animals.Foods (Basel, Switzerland) · 2022Review
- Ligilactobacillus salivarius functionalities, applications, and manufacturing challenges.Applied microbiology and biotechnology · 2022Review
- A meta-analysis ofFrontiers in veterinary science · 2022Article
- Supplementation of nano-zinc in lower doses as an alternative to pharmacological doses of ZnO in weanling pigs.Journal of animal science and technology · 2022Article
- Lactobacillus salivarius and Lactobacillus agilis feeding regulates intestinal stem cells activity by modulating crypt niche in hens.Applied microbiology and biotechnology · 2021Article
- Probiotics and Postbiotics as Substitutes of Antibiotics in Farm Animals: A Review.Animals : an open access journal from MDPI · 2021Review
- Effects of Different Fermented Feeds on Production Performance, Cecal Microorganisms, and Intestinal Immunity of Laying Hens.Animals : an open access journal from MDPI · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study determined the effects of Lactobacillus salivarius (LS) administered early in the life of suckling piglets on their growth performance, gut morphology, and gut microbiota. Thirty litters of 3-day-old crossbreed piglets were randomly assigned to one of the three treatments, and treatments were commenced on day 3 after birth. During the whole period of the experiment, the piglets were kept with their mothers and left to suckle ad libitum while being supplemented with a milk formula with or without the bacterial probiotic supplemented. The control group (CON) was not treated with probiotics, the HLS group was treated with LS144 (HLS) screened from feces of fast-growing pigs with high body mass index (BMI) while the NLS group was supplemented with LS160 (NLS) screened from feces obtained from pigs of normal BMI. At the weaning time, a higher abundance of Actinobacteria, Lentisphaerae, and Elusimicrobia phyla were observed in NLS piglets, whereas the abundance of Fibrobacteres phylum was significantly reduced in NLS and HLS piglets compared with the CON. A greater abundance of Lactobacillus was detected in the HLS treatment compared with the CON. The abundance of Bacteroides and Fibrobacter was higher in the CON piglets compared with the HLS and NLS piglets. Compared with the CON group, the oral administration of LS significantly increased the number of Lactobacillus and villus height in the duodenum, jejunum, and ileum. Moreover, the villus height of the duodenum was significantly improved in the HLS treatment compared with the NLS treatment. Based on the findings in the neonatal piglet model, we suggest that oral supplementation of LS, particularly LS isolated from high BMI pigs, could be beneficial by improving the intestinal villus height.
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