Evidence map›Paper›PMID 33762405›Full record

ArticleJournal of neurointerventional surgery2022

Dynamics of cerebral perfusion and oxygenation parameters following endovascular treatment of acute ischemic stroke.

Gianluca Brugnara, Christian Herweh, Ulf Neuberger, Mikkel Bo Hansen, Christian Ulfert, Mustafa Ahmed Mahmutoglu, Martha Foltyn, Simon Nagel, Silvia Schönenberger, Sabine Heiland and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurointerventional surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Gianluca BrugnaraDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.ORCID http://orcid.org/0000-0003-2461-1407
Christian HerwehDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Ulf NeubergerDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.ORCID http://orcid.org/0000-0002-3085-3886
Mikkel Bo HansenCenter of Functionally Integrative Neuroscience and MINDLab, Aarhus Universitet, Aarhus, Midtjylland, Denmark.
Christian UlfertDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Mustafa Ahmed MahmutogluDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Martha FoltynDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Simon NagelDepartment of Neurology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Silvia SchönenbergerDepartment of Neurology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Sabine HeilandDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Peter Arthur RinglebDepartment of Neurology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Martin BendszusDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Markus MöhlenbruchDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Johannes Alex Rolf PfaffDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.ORCID http://orcid.org/0000-0003-0672-5718
Philipp VollmuthDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany philipp.vollmuth@med.uni-heidelberg.de.ORCID http://orcid.org/0000-0002-6224-0064
Heidelberg University · DEAarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe studied the effects of endovascular treatment (EVT) and the impact of the extent of recanalization on cerebral perfusion and oxygenation parameters in patients with acute ischemic stroke (AIS) and large vessel occlusion (LVO).

methodsForty-seven patients with anterior LVO underwent computed tomography perfusion (CTP) before and immediately after EVT. The entire ischemic region (T

resultsThe T

conclusionsOur study demonstrates that the ischemic penumbra is the key target of successful EVT in patients with AIS and largely determines its efficacy on a tissue level. Furthermore, we confirm the validity of the mTICI score as a surrogate parameter of interventional success on a tissue perfusion level.

Indexed as

Brain IschemiaIschemic StrokeStrokeCerebrovascular CirculationHumansPerfusionangiographyCT perfusioninterventionstrokethrombectomy

Identifiers

PMID33762405
PMCPMC8785045
OpenAlexW3138350223

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.