Evidence map›Paper›PMID 33762269›Full record

ArticleBMJ case reports2021

Bone mineral density changes in a free vascularised fibular graft in the distal femoral bone after osteosarcoma in a 10-year-old boy: a 7-year follow-up.

Andrea René Jørgensen, Peter Holmberg Jørgensen, Birgitte Jul Kiil, Maiken Stilling

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Osteosarcoma in Children: Not Only Chemotherapy.Pharmaceuticals (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrea René JørgensenOrthopaedic Research Unit, Aarhus University Hospital, Aarhus N, Denmark anjo@clin.au.dk.
Peter Holmberg JørgensenDepartment of Orthopedic Surgery, Aarhus Universitetshospital, Aarhus N, Region Midt, Denmark.
Birgitte Jul KiilDepartment of Plastic Surgery, Aarhus University Hospital, Aarhus N, Denmark.
Maiken StillingDepartment of Orthopedic Surgery, Aarhus Universitetshospital, Aarhus N, Region Midt, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 10-year-old boy presented with continuous reports of pain located to the left knee. Imaging revealed a sclerotic process in the left distal femur, and biopsies were consistent with chondroblastic osteosarcoma. As part of standard treatment the patient underwent neoadjuvant chemotherapy followed by limb sparring surgery and adjuvant chemotherapy. The entire tumour was excised and femoral bone reconstruction was performed with a double barrel free vascularised fibular graft. Bone mineral density (BMD) can be decreased in childhood survivors of cancer. The patient was followed for 7 years with dual-energy X-ray absorptiometry scans in order to assess BMD and graft adaption. Despite two accidental fractures to the graft region local and global BMD underwent an overall increase. Approximately 7 years after tumour resection the patient had a global Z-score of 0.2, which is considered within normal range.

Indexed as

Bone NeoplasmsOsteosarcomaAbsorptiometry, PhotonBone DensityChildFemurFollow-Up StudiesHumansMalecancer interventionorthopaedicsosteoporosispaediatric oncology

Identifiers

PMID33762269
PMCPMC7993341

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.