Evidence map›Paper›PMID 33762065›Full record

ArticleBJPsych open2021

Comparing psychotropic medication prescribing in personality disorder between general mental health and psychological services: retrospective cohort study.

Giouliana Kadra-Scalzo, Jacqueline Garland, Stephen Miller, Chin-Kuo Chang, Marcella Fok, Richard D Hayes, Paul Moran, Hitesh Shetty, Allan H Young, Robert Stewart

Open access · goldAbstract read
In one paragraph

Article in BJPsych open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Giouliana Kadra-ScalzoInstitute of Psychiatry, Psychology and Neuroscience, King's College London, UK.ORCID https://orcid.org/0000-0003-3182-905X
Jacqueline GarlandCroydon Personality Disorder Service, South London and Maudsley NHS Foundation Trust, UK.
Stephen MillerCroydon Personality Disorder Service, South London and Maudsley NHS Foundation Trust, UK.
Chin-Kuo ChangInstitute of Psychiatry, Psychology and Neuroscience, King's College London, UK; Global Health Program, College of Public Health, National Taiwan University, Taiwan; and Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taiwan.
Marcella FokInstitute of Psychiatry, Psychology and Neuroscience, King's College London, UK; and Waterview Centre, Central and North West London NHS Foundation Trust, UK.ORCID https://orcid.org/0000-0002-6432-4392
Richard D HayesInstitute of Psychiatry, Psychology and Neuroscience, King's College London, UK.
Paul MoranCentre for Academic Mental Health, Department of Population Health Sciences, Bristol Medical School, University of Bristol, UK.
Hitesh ShettyBRC Nucleus, South London and Maudsley NHS Foundation Trust, UK.
Allan H YoungInstitute of Psychiatry, Psychology and Neuroscience, King's College London, UK.ORCID https://orcid.org/0000-0003-2291-6952
Robert StewartInstitute of Psychiatry, Psychology and Neuroscience, King's College London, UK; and BRC Nucleus, South London and Maudsley NHS Foundation Trust, UK.ORCID https://orcid.org/0000-0002-4435-6397
King's College London · GBSouth London and Maudsley NHS Foundation Trust · GBNational Taiwan University · TWUniversity of Bristol · GB

Funding

Medical Research Council MC_PC_17214
6 · The paper itself

Abstract

backgroundAlthough no drugs are licensed for the treatment of personality disorder, pharmacological treatment in clinical practice remains common.

aimsThis study aimed to estimate the prevalence of psychotropic drug use and associations with psychological service use among people with personality disorder.

methodUsing data from a large, anonymised mental healthcare database, we identified all adult patients with a diagnosis of personality disorder and ascertained psychotropic medication use between 1 August 2015 and 1 February 2016. Multivariable logistic regression models were constructed, adjusting for sociodemographic, clinical and service use factors, to examine the association between psychological services use and psychotropic medication prescribing.

resultsOf 3366 identified patients, 2029 (60.3%) were prescribed some form of psychotropic medication. Patients using psychological services were significantly less likely to be prescribed psychotropic medication (adjusted odds ratio 0.48, 95% CI 0.39-0.59, P<0.001) such as antipsychotics, benzodiazepines and antidepressants. This effect was maintained following several sensitivity analyses. We found no difference in the risk for mood stabiliser (adjusted odds ratio 0.79, 95% CI 0.57-1.10, P = 0.169) and multi-class psychotropic use (adjusted odds ratio 0.80, 95% CI 0.60-1.07, P = 0.133) between patients who did and did not use psychological services.

conclusionsPsychotropic medication prescribing is common in patients with personality disorder, but significantly less likely in those who have used psychological services. This does not appear to be explained by differences in demographic, clinical and service use characteristics. There is a need to develop clear prescribing guidelines and conduct research in clinical settings to examine medication effectiveness for this population.

Indexed as

general mental healthmedication prescribingPersonality disorderpsychological servicespsychotropics

Identifiers

PMID33762065
PMCPMC8058890
OpenAlexW3136376398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.