Evidence map›Paper›PMID 33761783›Full record

ArticlePalliative medicine2021

Willingness and concerns of transfusion-dependent hematological patients toward the option of home transfusion therapy.

Liza Barki-Harrington, Orna Baron-Epel, Adir Shaulov, Luiza Akria, Yossef Barshay, Najib Dally, Dana Deshet, Tsofia Inbar, Maya Koren-Michowitz, Merav Leiba and 9 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Palliative medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07121140 (A Pilot Study of Home Blood Transfusions for Patient With Cancer Who Have Transfusion Dependent Cytopenias), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07121140 narecruitingnot on this mapstarted 2025, after this paper: background citation

A Pilot Study of Home Blood Transfusions for Patient With Cancer Who Have Transfusion Dependent Cytopenias

TypeinterventionalSponsorThomas Jefferson UniversityRan2025 to 2027Enrolled30ConditionsHematologic Malignancy, Myelodysplastic Syndromes, Acute Myeloid Leukemia, Transfusion Dependent CytopeniasArmsHome Blood Transfusion
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Bringing the hospital home: exploring the challenges and perspectives of healthcare professionals on home treatment in hemato-oncology: a qualitative analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 10 institutions in 1 country.

Liza Barki-HarringtonDepartment of Human Biology, University of Haifa, Haifa, Israel.ORCID 0000-0002-9572-6490
Orna Baron-EpelSchool of Public Health, University of Haifa, Haifa, Israel.
Adir ShaulovDepartment of Hematology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Luiza AkriaBlood Bank and Molecular Hematology Laboratory, Galilee Medical Center, Nahariya, Israel.
Yossef BarshayDepartment of Hematology, Barzilai University Medical Center, Ashkelon, Israel.
Najib DallyFaculty of Medicine in the Galilee, Bar Ilan University, Safed, Israel.
Dana DeshetDepartment of Hematology, Edith Wolfson Medical Center, Holon, Israel.
Tsofia InbarDepartment of Hematology, Rambam Health Care Campus, Haifa, Israel.
Maya Koren-MichowitzSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Merav LeibaFaculty of Health Sciences, Ben Gurion University of the Negev, Be'er-Sheva, Israel.
Yakir MosheSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Lev ShvidelHematology Institute, Kaplan Medical Center, Rehovoth, Israel.
Tamar TadmorHematology Unit, Bnai Zion Medical Center, Israel.
Shai YagenahFaculty of Medicine in the Galilee, Bar Ilan University, Safed, Israel.
Miri ZektserFaculty of Health Sciences, Ben Gurion University of the Negev, Be'er-Sheva, Israel.
Meir PreisThe Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel.
Ilana HellmanSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Vered YahalomSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Ariel AvivHematology Unit, HaEmek Medical Center, Afula, Israel.
Tel Aviv University · ILBar-Ilan University · ILBen-Gurion University of the Negev · ILUniversity of Haifa · ILBnai Zion Medical Center · ILCarmel Medical Center · ILEmek Medical Center · ILHadassah Medical Center · ILKaplan Medical Center · ILRambam Health Care Campus · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOne of the main obstacles of providing home-based palliative care to transfusion-dependent hematology patients is the lack of home transfusions services. While healthcare professionals are concerned with safety and cost of home transfusions, the attitude of the patients toward home transfusions are mostly unknown.

aimTo obtain quantitative data regarding the willingness and concerns of transfusion-dependent patients with hematological diseases toward the option of home transfusions.

designA cross sectional survey including a self-administered questionnaire in one of the three main spoken languages in Israel was administered to patients in 17 hospital hematology outpatient clinics between May 2019 and March 2020.

resultsAbout 52% of 385 patients that participated in the survey preferred home transfusions to hospital transfusions. Gender, age, education, or type of disease were not associated with preference for home transfusions, nor were hospital location or its size. The likelihood to prefer home transfusions was significantly higher among the Hebrew-speakers and those who had not experienced adverse effects previously. The most significant factor associated with preference of home transfusions was a perceived negative effect of hospital-based transfusion on quality of life. The main reason to reject home transfusions was fear of possible adverse effects and concerns over losing contact with the medical staff at the treating hospital.

conclusionThese data suggest that a significant portion of transfusion-dependent patients in Israel view home transfusions as a preferred treatment option and that its successful implementation requires maintaining ongoing contact with the treating hospital.

Indexed as

Home Care ServicesQuality of LifeBlood TransfusionCross-Sectional StudiesHumansSurveys and Questionnairesbloodhematologyhome carepatient focused carephysician patient relationsTransfusion

Identifiers

PMID33761783
PMCPMC8114422
OpenAlexW3137430181

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.