ArticleArteriosclerosis, thrombosis, and vascular biology2021
Nonclassical Monocytes (CD14dimCD16+) Are Associated With Carotid Intima-Media Thickness Progression for Men but Not Women: The Multi-Ethnic Study of Atherosclerosis-Brief Report.
Open access · bronzeAbstract readComparative StudyMulticenter Study
In one paragraph
Article in Arteriosclerosis, thrombosis, and vascular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 24% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Association of immune cell subsets with incident heart failure in two population-based cohorts.ESC heart failure · 2022Pooled it
- Research progress on serological indices and their clinical application in rheumatoid arthritis.Journal of clinical laboratory analysis · 2022Pooled it
- Association of Monocyte Subsets with Carotid Artery Stenosis Severity.Medicina (Kaunas, Lithuania) · 2026Article
- Aging-related immune phenotypes are associated with subclinical coronary atherosclerosis in a middle-aged population: a subcohort of the Swedish CArdioPulmonary bioImage Study.Immunity & ageing : I & A · 2026Article
- Monocytes Defined by Platelet Interactions and Oxidative Stress Signaling Underlie HIV-Associated Atherosclerosis.Journal of the American Heart Association · 2026Article
- Aging-associated immune signature as a predictor of mortality in end-stage renal disease: results from the longitudinal iESRD study.Immunity & ageing : I & A · 2025Article
- Associations of Immune Cell Subsets With Coronary Artery Calcium Incidence and Progression in the Multi-Ethnic Study of Atherosclerosis.Journal of the American Heart Association · 2025Observational
- Association of Immune Cell Subsets With Longevity: The Cardiovascular Health Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Associations of circulating T cell subsets with endothelial function: the Multi-Ethnic Study of Atherosclerosis.American journal of physiology. Heart and circulatory physiology · 2025Observational
- Changes in monocyte subsets are associated with an increased risk of AAA and are surrogate markers for AAA morphology in patients with late-stage disease.Frontiers in immunology · 2025Observational
- Associations of circulating T-cell subsets with carotid artery stiffness: the multiethnic study of atherosclerosis.American journal of physiology. Heart and circulatory physiology · 2025Article
- Associations of circulating T-cell subsets in carotid artery stiffness: the Multi-Ethnic Study of Atherosclerosis.medRxiv : the preprint server for health sciences · 2024Article
- Macrophage profiling in atherosclerosis: understanding the unstable plaque.Basic research in cardiology · 2024Review
- Investigating peripheral blood monocyte and T-cell subsets as non-invasive biomarkers for asymptomatic hepatic steatosis: results from the Multi-Ethnic Study of Atherosclerosis.Frontiers in immunology · 2024Article
- Dietary Effects on Monocyte Phenotypes in Subjects With Hypertriglyceridemia and Metabolic Syndrome.JACC. Basic to translational science · 2023Article
- By what molecular mechanisms do social determinants impact cardiometabolic risk?Clinical science (London, England : 1979) · 2023Review
- The CCR2Journal of cardiovascular development and disease · 2022Article
- LDL associates with pro-inflammatory monocyte subset differentiation and increases in chemokine receptor profile expression in African Americans.International journal of cardiology · 2022Article
- Monocyte subsets, T cell activation profiles, and stroke in men and women: The Multi-Ethnic Study of Atherosclerosis and Cardiovascular Health Study.Atherosclerosis · 2022Article
- Association of immune cell subsets with cardiac mechanics in the Multi-Ethnic Study of Atherosclerosis.JCI insight · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 10 institutions in 4 countries.
Matthew J FeinsteinDepartments of Medicine and Preventive Medicine, Northwestern University, Chicago, IL (M.J.F.).
Margaret F DoyleUniversity of Vermont, Burlington (M.F.D., S.A.H., R.P.T., N.C.O.).
James H SteinUniversity of Wisconsin, Madison (J.H.S.).
Colleen M SitlaniUniversity of Washington, Seattle (C.M.S., A.E.F., S.R.H., K.R., R.A.K.).
Alison E FohnerUniversity of Washington, Seattle (C.M.S., A.E.F., S.R.H., K.R., R.A.K.).
Sally A HuberUniversity of Vermont, Burlington (M.F.D., S.A.H., R.P.T., N.C.O.).
Alan L LandayRush University Medical Center, Chicago, IL (A.L.L.).
Susan R HeckbertUniversity of Washington, Seattle (C.M.S., A.E.F., S.R.H., K.R., R.A.K.).
Kenneth RiceUniversity of Washington, Seattle (C.M.S., A.E.F., S.R.H., K.R., R.A.K.).
Richard A KronmalUniversity of Washington, Seattle (C.M.S., A.E.F., S.R.H., K.R., R.A.K.).
Catherine HedrickLa Jolla Institute of Immunology, CA (C.H.).
Ani ManichaikulUniversity of Virginia, Charlottesville (A.M., C.M., S.R.).
Coleen McNamaraUniversity of Virginia, Charlottesville (A.M., C.M., S.R.).
Stephen RichUniversity of Virginia, Charlottesville (A.M., C.M., S.R.).
Russell P TracyUniversity of Vermont, Burlington (M.F.D., S.A.H., R.P.T., N.C.O.).
Nels C OlsonUniversity of Vermont, Burlington (M.F.D., S.A.H., R.P.T., N.C.O.).
Bruce M PsatyCardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Services, University of Washington, Seattle (B.M.P.).
Joseph A C DelaneyUniversity of Manitoba, Winnipeg, Canada (J.A.C.D.).
University of Vermont · USUniversity of Washington · USUniversity of Virginia · USCerner (United States) · USJames Madison University · USLa Jolla Institute for Immunology · USNorthwestern University · USRush University Medical Center · USUnited States Nuclear Regulatory Commission · USUniversity of Manitoba · CA
Funding
Innate and adaptive immune-cell densities as risk factors for heart failureR01HL135625 · NHLBI · UNIVERSITY OF WASHINGTON · PI PSATY, BRUCE M, TRACY, RUSSELL P · 2018 to 2021
$2.8MT-cell subsets as CVD risk factors in CHS and MESAR01HL120854 · NHLBI · UNIVERSITY OF WASHINGTON · PI PSATY, BRUCE M, TRACY, RUSSELL P · 2014 to 2017
$2.6MImmune Activation and Immunosenescence Biomarkers and Cardiovascular Disease RiskR00HL129045 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI OLSON, NELS C. · 2018 to 2020
$745kNHLBI NIH HHS R00 HL129045NHLBI NIH HHS R01 HL120854NHLBI NIH HHS R01 HL135625
Abstract
[Figure: see text].
Indexed as
Carotid Intima-Media ThicknessAgedAged, 80 and overBiomarkersCarotid Artery DiseasesCase-Control StudiesDisease ProgressionFemaleFlow CytometryGPI-Linked ProteinsHumansImmunophenotypingLipopolysaccharide ReceptorsMaleMiddle AgedMonocytesBiomarkersCD14 protein, humanFCGR3B protein, humanGPI-Linked ProteinsLipopolysaccharide ReceptorsReceptors, IgGatherosclerosiscarotid intima-media thicknessepidemiologyinflammationmonocytes
Identifiers
What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.