ArticleJournal of the neurological sciences2021
Risk factors and outcomes of hospitalized stroke patients in Lusaka, Zambia.
Article in Journal of the neurological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Trends and Clinical Characteristics of HIV and Cerebrovascular Disease in Low- and Middle-Income Countries (LMICs) Between 1990 and 2021.Current HIV/AIDS reports · 2022Pooled it
- Determinants and long-term outcomes of treatment delays in young and middle-aged acute ischemic stroke patients: a prospective cohort study.BMC neurology · 2026Article
- Comprehensive analysis of neurological disease patterns in a fragile health system in Somalia.Scientific reports · 2025Article
- Characteristics of adults with first-ever stroke vs. recurrent stroke at the university teaching Hospital in Lusaka, Zambia.Journal of the neurological sciences · 2025Article
- Kigelia africana fruit fractions inhibit in vitro alpha-glucosidase activity: a potential natural alpha-glucosidase inhibitor.BMC complementary medicine and therapies · 2024Article
- Stroke characteristics and outcomes in urban Tanzania: Data from the Prospective Lake Zone Stroke Registry.International journal of stroke : official journal of the International Stroke Society · 2024Article
- Examining the influence of global smoking prevalence on stroke mortality: insights from 27 countries across income strata.BMC public health · 2024Article
- Developing Systems for Cardiac and Stroke Care in Zambia.Journal of the American Heart Association · 2024Article
- Article
- Biological Sex Differences in Risk Factors and Outcomes Among Hospitalized Adults With Stroke in Lusaka, Zambia.Neurology · 2023Article
- The Burden and In-Hospital Mortality of Stroke Admissions at a Tertiary Level Hospital in Namibia: A Retrospective Cohort Study.Stroke research and treatment · 2023Article
- Hypertension among persons living with HIV-Zambia, 2021; A cross-sectional study of a national electronic health record system.PLOS global public health · 2023Article
- Stroke unit and Neurocritical Care Unit for acute neurological diseases in the USL Toscana Centro: a pilot model of Santo Stefano Hospital in Prato.Frontiers in stroke · 2023Article
- Providing Neurocritical Care in Resource-Limited Settings: Challenges and Opportunities.Neurocritical care · 2022Review
- Prevalence and Characteristics of HIV-Associated Stroke in a Tertiary Hospital Setting in South Africa.Neurology · 2022Article
- Predictors of in-hospital and 90-day post-discharge stroke mortality in Lusaka, Zambia.Journal of the neurological sciences · 2022Article
- Article
- Diagnostic Value of Image Features of Magnetic Resonance Imaging in Intracranial Hemorrhage and Cerebral Infarction.Contrast media & molecular imaging · 2022Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundLimited data exists about stroke risk factors and outcomes in sub-Saharan African countries, including Zambia. We aim to fill this gap by describing features of hospitalized stroke patients at University Teaching Hospital (UTH), the national referral hospital in Lusaka, Zambia.
methodsWe conducted a retrospective study of consecutive adults with stroke admitted to UTH's inpatient neurology service from October 2018 to March 2019. Strokes were classified as ischemic or hemorrhagic based on CT scan results and unknown if CT scan was not obtained. Chi-square analyses and t-tests were used to compare characteristics between cohorts with differing stroke subtypes.
resultsAdults with stroke constituted 43% (n = 324) of all neurological admissions, had an average age of 60 ± 18 years, and 62% of the cohort was female. Stroke subtypes were 58% ischemic, 28% hemorrhagic, and 14% unknown. Hypertension was present in 80% of all strokes and was significantly associated with hemorrhagic stroke (p = 0.03). HIV was present in 18% of all strokes and did not significantly differ by stroke subtype. Diabetes (16%), heart disease (34%), atrial fibrillation (9%), and past medical history of stroke (22%) were all significantly more common in patients with ischemic stroke (p < 0.05). In-hospital mortality was 24% overall and highest among individuals with hemorrhagic strokes (33%, p = 0.005).
conclusionsThis Zambian stroke cohort is notable for its young age, significant HIV burden, high in-hospital mortality, and high rates of uncontrolled hypertension. Our results demonstrate Zambia's substantial stroke burden, significant contribution of HIV to stroke, and the need to improve primary stroke prevention.
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