Evidence map›Paper›PMID 33761235›Full record

ArticleACS synthetic biology2021

Light-Powered Reactivation of Flagella and Contraction of Microtubule Networks: Toward Building an Artificial Cell.

Raheel Ahmad, Christin Kleineberg, Vahid Nasirimarekani, Yu-Jung Su, Samira Goli Pozveh, Albert Bae, Kai Sundmacher, Eberhard Bodenschatz, Isabella Guido, Tanja Vidaković-Koch and 1 more

Abstract read
In one paragraph

Article in ACS synthetic biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Let There be Light! Light as an Engine and Regulator in Synthetic Cells.Angewandte Chemie (International ed. in English) · 2026
    Review
  3. Photocatalytic Biohybrid Vesicles.Chemical reviews · 2026
    Review
  4. Quantification of flagellar gait changes with combined shape mode analysis and swimming simulations.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025
    Article
  5. Thermally Driven Dynamic Behaviors in Polymeric Vesicles.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Raheel AhmadMax-Planck Institute for Dynamics and Self-Organization, Am Faßberg 17, 37077 Göttingen, Germany.ORCID 0000-0001-8313-7413
Christin KleinebergMax-Planck Institute for Dynamics of Complex Technical Systems, Sandtorstraße 1, 39106 Magdeburg, Germany.
Vahid NasirimarekaniMicrofluidics & BIOMICS Cluster UPV/EHU, University of the Basque Country UPV/EHU, 01006 Vitoria-Gasteiz, Spain.
Yu-Jung SuMax-Planck Institute for Dynamics and Self-Organization, Am Faßberg 17, 37077 Göttingen, Germany.
Samira Goli PozvehMax-Planck Institute for Dynamics and Self-Organization, Am Faßberg 17, 37077 Göttingen, Germany.
Albert BaeDepartment of Biomedical Engineering, University of Rochester, Rochester, New York 14627, United States.
Kai SundmacherMax-Planck Institute for Dynamics of Complex Technical Systems, Sandtorstraße 1, 39106 Magdeburg, Germany.ORCID 0000-0003-3251-0593
Eberhard BodenschatzMax-Planck Institute for Dynamics and Self-Organization, Am Faßberg 17, 37077 Göttingen, Germany.
Isabella GuidoMax-Planck Institute for Dynamics and Self-Organization, Am Faßberg 17, 37077 Göttingen, Germany.ORCID 0000-0002-1781-3767
Tanja Vidaković-KochMax-Planck Institute for Dynamics of Complex Technical Systems, Sandtorstraße 1, 39106 Magdeburg, Germany.ORCID 0000-0003-3896-3585
Azam GholamiMax-Planck Institute for Dynamics and Self-Organization, Am Faßberg 17, 37077 Göttingen, Germany.ORCID 0000-0002-9332-4551

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial systems capable of self-sustained movement with self-sufficient energy are of high interest with respect to the development of many challenging applications, including medical treatments, but also technical applications. The bottom-up assembly of such systems in the context of synthetic biology is still a challenging task. In this work, we demonstrate the biocompatibility and efficiency of an artificial light-driven energy module and a motility functional unit by integrating light-switchable photosynthetic vesicles with demembranated flagella. The flagellar propulsion is coupled to the beating frequency, and dynamic ATP synthesis in response to illumination allows us to control beating frequency of flagella in a light-dependent manner. In addition, we verified the functionality of light-powered synthetic vesicles in

Indexed as

Artificial CellsLightAdenosine TriphosphateAxonemeCell EngineeringCell MovementChlamydomonas reinhardtiiCiliaDyneinsEnergy MetabolismFlagellaKinesinsLiposomesPhotosynthesisSignal TransductionAdenosine TriphosphateDyneinsKinesinsLiposomes

Identifiers

PMID33761235
PMCPMC8218302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.