Evidence map›Paper›PMID 33761064›Full record

ArticleInternational journal of computer assisted radiology and surgery2021

Pre-surgery planning tool for estimation of resection volume to improve nasal breathing based on lattice Boltzmann fluid flow simulations.

M Berger, M Pillei, A Giotakis, A Mehrle, W Recheis, F Kral, M Kraxner, H Riechelmann, W Freysinger

Abstract read
In one paragraph

Article in International journal of computer assisted radiology and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Determinants of olfactory cleft targeting in intranasal aerosol delivery: a combined computational and experimental study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Review
  3. [Measurement of nasal septum area in 128 Chinese patients with nasal septum deviation].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

M BergerDepartment of Environmental, Process and Energy Engineering, MCI-The Entrepreneurial School, Innsbruck, Austria. manuel.berger@mci.edu.ORCID http://orcid.org/0000-0001-5026-6251
M PilleiDepartment of Environmental, Process and Energy Engineering, MCI-The Entrepreneurial School, Innsbruck, Austria.ORCID http://orcid.org/0000-0003-1459-7234
A GiotakisDepartment of Otorhinolaryngology-Head and Neck Surgery, Medical University of Innsbruck, Innsbruck, Austria.ORCID http://orcid.org/0000-0002-4162-4261
A MehrleDepartment of Mechatronics, MCI-The Entrepreneurial School, Innsbruck, Austria.
W RecheisUniversity Hospital of Radiology, Medical University Innsbruck, Innsbruck, Austria.ORCID http://orcid.org/0000-0002-1296-868X
F KralDepartment of Otorhinolaryngology-Head and Neck Surgery, Medical University of Innsbruck, Innsbruck, Austria.
M KraxnerDepartment of Environmental, Process and Energy Engineering, MCI-The Entrepreneurial School, Innsbruck, Austria.
H RiechelmannDepartment of Otorhinolaryngology-Head and Neck Surgery, Medical University of Innsbruck, Innsbruck, Austria.ORCID http://orcid.org/0000-0001-5013-6158
W FreysingerDepartment of Otorhinolaryngology-Head and Neck Surgery, Medical University of Innsbruck, Innsbruck, Austria.ORCID http://orcid.org/0000-0002-2833-3224

Funding

Medizinische Universität Innsbruck D-153110-019-014
6 · The paper itself

Abstract

purposeState-of-the-art medical examination techniques (e.g., rhinomanometry and endoscopy) do not always lead to satisfactory postoperative outcome. A fully automatized optimization tool based on patient computer tomography (CT) data to calculate local pressure gradient regions to reshape pathological nasal cavity geometry is proposed.

methodsFive anonymous pre- and postoperative CT datasets with nasal septum deviations were used to simulate the airflow through the nasal cavity with lattice Boltzmann (LB) simulations. Pressure gradient regions were detected by a streamline analysis. After shape optimization, the volumetric difference between the two shapes of the nasal cavity yields the estimated resection volume.

resultsAt LB rhinomanometry boundary conditions (bilateral flow rate of 600 ml/s), the preliminary study shows a critical pressure gradient of -1.1 Pa/mm as optimization criterion. The maximum coronal airflow ΔA  := cross-section ratio [Formula: see text] found close to the nostrils is 1.15. For the patients a pressure drop ratio ΔΠ  := (pre-surgery - virtual surgery)/(pre-surgery - post-surgery) between nostril and nasopharynx of 1.25, 1.72, -1.85, 0.79 and 1.02 is calculated.

conclusionsLB fluid mechanics optimization of the nasal cavity can yield results similar to surgery for air-flow cross section and pressure drop between nostril and nasopharynx. The optimization is numerically stable in all five cases of the presented study. A limitation of this study is that anatomical constraints (e.g. mucosa) have not been considered.

Indexed as

AdultComputer SimulationEndoscopyFemaleHumansMaleNasal CavityNasal SeptumNeoplasm StagingPattern Recognition, AutomatedPostoperative PeriodRespirationTomography, X-Ray ComputedBreathing improvementNasal cavityOptimizationPostoperative outcome

Identifiers

PMID33761064
PMCPMC8052247

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.