ArticleEJNMMI physics2021
Evaluation of the PETsys TOFPET2 ASIC in multi-channel coincidence experiments.
Article in EJNMMI physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- Multi-angle acquisition and 3D composite reconstruction for organ-targeted PET using planar detectors.Medical physics · 2025Article
- ASICs in PET: what we have and what we need.EJNMMI physics · 2025Review
- Depth-encoding using optical photon TOF in a prism-PET detector with tapered crystals.Medical physics · 2024Article
- PET Detectors Based on Multi-Resolution SiPM Arrays.IEEE transactions on radiation and plasma medical sciences · 2024Article
- 16-channel SiPM high-frequency readout with time-over-threshold discrimination for ultrafast time-of-flight applications.EJNMMI physics · 2023Article
- Timing, Energy, and Spatial Characterization of Highly Sampled Monolithic PET Detectors with Different Thicknesses.IEEE transactions on radiation and plasma medical sciences · 2023Article
- Interleaved signal multiplexing readout in depth encoding Prism-PET detectors.Medical physics · 2023Article
- A conformal TOF-DOI Prism-PET prototype scanner for high-resolution quantitative neuroimaging.Medical physics · 2023Article
- Technical opportunities and challenges in developing total-body PET scanners for mice and rats.EJNMMI physics · 2023Review
- Timing, Energy, and 3-D Spatial Resolution of the BING PET Detector Module.IEEE transactions on radiation and plasma medical sciences · 2023Article
- Advances in Detector Instrumentation for PET.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022Review
- Performance evaluation of side-by-side optically coupled monolithic LYSO crystals.Medical physics · 2022Article
- Update on latest advances in time-of-flight PET.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2020Review
- Development and initial characterization of a high-resolution PET detector module with DOI.Biomedical physics & engineering express · 2020Article
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4 authors.
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Abstract
backgroundAiming to measure the difference in arrival times of two coincident γ-photons with an accuracy in the order of 200ps, time-of-flight positron emission tomography systems commonly employ silicon photomultipliers (SiPMs) and high-resolution digitization electronics, application specific integrated circuits (ASICs). This work evaluates the performance of the TOFPET2 ASIC, released by PETsys Electronics S.A. in 2017, dependent on its configuration parameters in multi-channel coincidence measurements.
methodsSiPM arrays fabricated by different vendors (KETEK, SensL, Hamamatsu, Broadcom) were tested in combination with the ASIC. Scintillator arrays featuring different reflector designs and different configurations of the TOFPET2 ASIC software parameters were evaluated. The benchtop setup used is provided with the TOFPET2 ASIC evaluation kit by PETsys Electronics S.A.
resultsCompared to existing studies featuring the TOFPET2 ASIC, multi-channel performance results dependent on a larger set of ASIC configuration parameters were obtained that have not been reported to this extend so far. The ASIC shows promising CRTs down to 219.9 ps in combination with two Hamamatsu S14161-3050-HS-08 SiPM arrays (128 channels read out, energy resolution 13.08%) and 216.1 ps in combination with two Broadcom AFBR-S4N44P643S SiPM arrays (32 channels read out, energy resolution 9.46%). The length of the trigger delay of the dark count suppression scheme has an impact on the ASIC performance and can be configured to further improve the coincidence resolution time. The integrator gain configuration has been investigated and allows an absolute improvement of the energy resolution by up to 1% at the cost of the linearity of the energy spectrum.
conclusionMeasuring up to the time-of-flight performance of state-of-the-art positron emission tomography (ToF-PET) systems while providing a uniform and stable readout for multiple channels at the same time, the TOFPET2 ASIC is treated as promising candidate for the integration in future ToF-PET systems.
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