Evidence map›Paper›PMID 33760983›Full record

ReviewCurrent pain and headache reports2021

Reducing New Persistent Opioid Use After Surgery: A Review of Interventions.

Stacey Burns, Richard Urman, Rachel Pian, Oscar Jim Michael Coppes

Erratum issuedAbstract readReview
In one paragraph

Review in Current pain and headache reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Opioid consumption after lower limb amputation in Medicare beneficiaries.PM & R : the journal of injury, function, and rehabilitation · 2025
    Article
  7. Review
  8. Persistent Opioid Use Following Major Orthopedic Surgery.Current pain and headache reports · 2025
    Review
  9. Review
  10. Article
  11. Predictors of new persistent opioid use after surgery in adults.Anesthesiology and perioperative science · 2025
    Article
  12. Article
  13. Opioid stewardship.BJA education · 2023
    Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Stacey BurnsDepartment of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA. sburns0@bwh.harvard.edu.ORCID http://orcid.org/0000-0001-8878-6834
Richard UrmanDepartment of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA.
Rachel PianDepartment of Biology, Boston University, Boston, MA, USA.
Oscar Jim Michael CoppesDepartment of Anesthesia and Critical Care, University of Chicago, Chicago, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis review aims to summarize interventions used in the perioperative period to reduce the development of new persistent postoperative opioid use in opioid-naïve patients. RECENT

findingsThe development of new persistent opioid use after surgery has recently been identified as a common postoperative complication. The existing literature suggests that interventions across the continuum of care have been shown to decrease the incidence of new persistent postoperative opioid use. Specific preoperative, intraoperative, and postoperative interventions will be reviewed, as well as the use of clinical pathways and protocols that span throughout the perioperative period. Common to many of these interventions include the use of multimodal analgesia throughout the perioperative period and an emphasis on a patient-centered, evidence-based approach to the perioperative pain management plan. While the incidence of new persistent postoperative opioid use appears to be high, the literature suggests that there are both small- and large-scale interventions that can be used to reduce this. Technological advances including prescription monitoring systems and mobile applications have enabled studies to monitor opioid consumption after discharge. Interventions that occur preoperatively, such as patient education and expectation setting regarding postoperative pain management, and interventions that occur postoperatively, such as the implementation of procedure-specific, evidence-based prescribing guidelines and protocols, have been shown to reduce post-discharge opioid consumption. The use of multimodal analgesia and opioid-sparing adjuncts throughout the perioperative period is central to many of these interventions and has essentially become standard of care for management of perioperative pain.

Indexed as

Analgesics, OpioidCritical PathwaysEnhanced Recovery After SurgeryHumansOpioid-Related DisordersPain ManagementPerioperative CarePostoperative PainAnalgesics, OpioidMultidisciplinary pain managementMultimodal analgesiaPerioperative opioid reductionPersistent postoperative opioid usePostsurgical opioids

Identifiers

PMID33760983
PMCPMC7990836

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.