ArticlePloS one2021
Transfusion-Transmitted Infections and associated risk factors at the Northern Zone Blood Transfusion Center in Tanzania: A study of blood donors between 2017 and 2019.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Pooled it
- Systematic review of prevalence and risk factors of transfusion transmissible infections among blood donors, and blood safety improvements in Southern Africa.Transfusion medicine (Oxford, England) · 2023Pooled it
- Factors influencing candidate blood donors' deferral, retention and blood safety in Tanzania: A prospective cross-sectional study.Vox sanguinis · 2026Article
- Seroprevalence and Risk Factors for Transfusion-transmitted Infections among Blood Donors in Dera Ismail Khan, Pakistan: A Single-Center Cross-sectional Study.Journal of epidemiology and global health · 2026Observational
- Association between ABO/Rh blood groups and transfusion-transmitted infections among Turkish blood donors: a comprehensive demographic analysis (2015-2021).BMC infectious diseases · 2026Article
- Knowledge, Attitude, Practice and Associated Factors Regarding Safe Blood Donation Among Students of Public Universities in Afghanistan: A Cross-Sectional Study.Health science reports · 2026Article
- Optimizing healthcare for blood donors at risk of transfusion-transmissible infections: pre-implementation mixed methods protocol.Global health action · 2025Article
- COVID-19 pandemic impact on blood donations and discards from screening tests for transfusion-transmitted infections in a Brazil Brazilian metropolitan area.Transfusion medicine (Oxford, England) · 2025Article
- Article
- Blood donors as a sentinel population for real-time malaria surveillance using the Sysmex XN-31: a one-year review from the National Blood Transfusion Centre in Burkina Faso.Malaria journal · 2025Article
- Investigating the prevalence and determinants of HIV, HBV, HCV, andVirusdisease · 2025Article
- A comparative analysis between NAT and chemiluminescence in detection of transfusion transmitted viruses in two main university blood transfusion centers.Scientific reports · 2025Article
- Prevalence trends of transfusion-transmitted infections at a tertiary private hospital blood bank in Uganda: a retrospective 6-year review (2017-2022).BMC infectious diseases · 2025Article
- Seroprevalence of HIV, HBV, HCV and Syphilis among blood donors in a Nigerian tertiary medical centre.BMC infectious diseases · 2025Article
- Article
- The Issue of Screening for Transfusion-Transmitted Infections in Sub-Saharan Africa Presents Several Challenges: A Review.Advances in hematology · 2025Review
- Prevalence and Factors Associated with transfusion-transmissible infections among blood donors in Arua regional blood bank, Uganda.BMC infectious diseases · 2024Article
- Causes of pre and post-donation deferrals among blood donors, at Kwale Satellite Blood Transfusion Center, Kwale County, Kenya, 2018-2022.BMC public health · 2024Article
- COVID-19 impact on blood donor characteristics and seroprevalence of transfusion-transmitted infections in southern Thailand between 2018 and 2022.Scientific reports · 2024Article
- Transfusion transmitted infections among blood donors of Kamenge Teaching Hospital blood bank in Burundi.African health sciences · 2024Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBlood transfusion saves many people every year that would otherwise have died. The present study aimed to provide an update and insightful information regarding prevalence of the common Transfusion-Transmitted Infections (TTIs) and associated factors among blood donors in Tanzania.
methodsThis was a cross-sectional study involving retrospectively collected data of blood donors from the Tanzania Northern Zone Blood Transfusion Center between 2017 and 2019. Descriptive statistics were performed to describe characteristics of the blood donors. Univariable and multivariable logistic regression analyses were performed to determine association between prevalence of TTIs and socio-demographic factors. P-value <0.05 was considered statistically significant.
resultsA total of 101, 616 blood donors were included in the present study of which 85,053(83.7%) were males while 16,563 (16.3%) were females. Of all participants, the majority 45,400 (44.7%) were aged between 18 and 25 years; 79,582 (78.3%) were voluntary non-remunerated donors while 22,034 (21.7%) were replacement donors. The vast majority of them 99,626 (98%) were first time blood donors while 1990 (2%) were multiple donors. The overall prevalence of TTIs was 10.1% (10,226 out of 101,616) of which the leading was HBV accounting for 5.1% (5,264 out of 101,616). Being a replacement donor was associated with all the four types of TTIs: HIV (AOR = 1.22, 95% CI = 1.10-1.35), HBV (AOR = 1.35, 95% CI = 1.27-1.44), HCV (AOR = 1.28, 95% CI = 1.12-1.46), and syphilis (AOR = 1.33, 95% CI = 1.20-1.48).
conclusionsOur study has demonstrated that Tanzania has relatively high prevalence of TTIs compared to some countries in Sub-Saharan Africa. HBV infection seems to be the most common infection among blood donors and replacement blood donors are at a higher risk of harboring the commonest TTIs among blood donors.
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