ArticlePLoS neglected tropical diseases2021
Chagas disease screening in pregnant Latin American women: Adherence to a systematic screening protocol in a non-endemic country.
Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- High awareness, inadequate practices: a cross-sectional KAP study on Chagas disease in an endemic Venezuelan community.Tropical medicine and health · 2025Article
- Chagas Disease in the 21st Century: Global Spread, Ecological Shifts, and Research Frontiers.Biology · 2025Review
- Prevalence, knowledge, attitudes, and practices regarding Chagas disease in Guanare, Venezuela: a cross-sectional study.Parasites & vectors · 2025Article
- Congenital transmission of Chagas disease: The role of newborn therapy on the disease's dynamics.PloS one · 2024Article
- Cytokine profile levels and their relationship with parasitemia and cardiomyopathy in people with Chagas disease in Spain. A prospective observational study.Parasitology research · 2023Observational
- Chagas Disease in Europe.Tropical medicine and infectious disease · 2023Review
- A Questionnaire Integrated with the Digital Medical Record Improved the Coverage of a Control Program for Congenital Chagas Disease in Tuscany, Italy.Microorganisms · 2023Article
- Worldwide Control and Management of Chagas Disease in a New Era of Globalization: a Close Look at Congenital Trypanosoma cruzi Infection.Clinical microbiology reviews · 2022Review
- Revisiting Chagas' disease diagnostic strategies in light of different scenarios of Trypanosoma cruzi infection.Memorias do Instituto Oswaldo Cruz · 2022Article
- Chagas Disease-Related Mortality in Spain, 1997 to 2018.Microorganisms · 2021Article
- Community-based screening of Chagas disease among Latin American migrants in a non-endemic country: an observational study.Infectious diseases of poverty · 2021Observational
- Is It Possible to Intervene in the Capacity ofFrontiers in immunology · 2021Review
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Authors and funding
22 authors.
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Abstract
backgroundChagas disease (CD) is a chronic parasitic disease caused by Trypanosoma cruzi and is endemic to continental Latin America. In Spain, the main transmission route is congenital. We aimed to assess adherence to regional recommendations of universal screening for CD during pregnancy in Latin American women in the province of Alicante from 2014 to 2018. METHODOLOGY/PRINCIPAL
findingsRetrospective quality study using two data sources: 1) delivery records of Latin American women that gave birth in the 10 public hospitals of Alicante between January 2014 and December 2018; and 2) records of Chagas serologies carried out in those centers between May 2013 and December 2018. There were 3026 deliveries in Latin American women during the study period; 1178 (38.9%) underwent CD serology. Screening adherence ranged from 17.2% to 59.3% in the different health departments and was higher in Bolivian women (48.3%). Twenty-six deliveries (2.2%) had a positive screening; CD was confirmed in 23 (2%) deliveries of 21 women. Bolivians had the highest seroprevalence (21/112; 18.7%), followed by Colombians (1/333; 0.3%) and Ecuadorians (1/348; 0.3%). Of 21 CD-positive women (19 Bolivians, 1 Colombian, 1 Ecuadorian), infection was already known in 12 (57.1%), and 9 (42.9%) had already been treated. Only 1 of the 12 untreated women (8.3%) was treated postpartum. Follow-up started in 20 of the 23 (87.0%) neonates but was completed only in 11 (47.8%); no cases of congenital transmission were detected. Among the 1848 unscreened deliveries, we estimate 43 undiagnosed cases of CD and 1 to 2 undetected cases of congenital transmission. CONCLUSIONS/SIGNIFICANCE: Adherence to recommendations of systematic screening for CD in Latin American pregnant women in Alicante can be improved. Strategies to strengthen treatment of postpartum women and monitoring of exposed newborns are needed. Currently, there may be undetected cases of congenital transmission in our province.
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