ArticlePloS one2021
Continued proportional age shift of confirmed positive COVID-19 incidence over time to children and young adults: Washington State March-August 2020.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Does baricitinib reduce mortality and disease progression in SARS-CoV-2 virus infected patients? A systematic review and meta analysis.Respiratory medicine · 2022Pooled it
- The burden of COVID-19 in primary care of Almaty, Kazakhstan, 2021-2022.Scientific reports · 2025Article
- Recurrent stroke admissions withWorld journal of virology · 2024Article
- SARS-CoV-2 clade dynamics and their associations with hospitalisations during the first two years of the COVID-19 pandemic.PloS one · 2024Article
- Parallel dynamics in the yield of universal SARS-CoV-2 admission screening and population incidence.Scientific reports · 2023Article
- Household Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 From Adult Index Cases With and Without Human Immunodeficiency Virus in South Africa, 2020-2021: A Case-Ascertained, Prospective, Observational Household Transmission Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Observational
- Impact of SARS-CoV-2 vaccination of children ages 5-11 years on COVID-19 disease burden and resilience to new variants in the United States, November 2021-March 2022: A multi-model study.Lancet regional health. Americas · 2023Article
- Estimating the infection burden of COVID-19 in Malaysia.PLoS neglected tropical diseases · 2022Article
- Investigation of COVID-19 infection in subjects with Klinefelter syndrome.Journal of endocrinological investigation · 2022Article
- Impact of SARS-CoV-2 vaccination of children ages 5-11 years on COVID-19 disease burden and resilience to new variants in the United States, November 2021-March 2022: a multi-model study.medRxiv : the preprint server for health sciences · 2022Article
- The Third Wave: Comparing Seasonal Trends in COVID-19 Patient Data at a Large Hospital System in New York City.Critical care explorations · 2022Article
- Physiological Network Is Disrupted in Severe COVID-19.Frontiers in physiology · 2022Article
- SARS-CoV-2 Epidemiology on a Public University Campus in Washington State.Open forum infectious diseases · 2021Article
- Global Temporal Patterns of Age Group and Sex Distributions of COVID-19.Infectious disease reports · 2021Article
- Data from the COVID-19 epidemic in Florida suggest that younger cohorts have been transmitting their infections to less socially mobile older adults.Review of economics of the household · 2020Article
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAs the coronavirus (COVID-19) epidemic passed initial infection peak in Washington State, phased re-opening lifted stay-at-home orders and restrictions leading to increased non-essential work, social activities and gathering, especially among younger persons.
methodsA longitudinal cohort analysis of Washington State Department of Health COVID-19 confirmed case age distribution 1) March-April 2020 (N = 13,934) and 2) March-August 2020 (N = 76,032) for proportional change over time using chi square tests for significance.
resultsFrom March 1st to April 19, 2020 COVID-19 age distribution shifted with a 10% decline in cases age 60 years and older and a 20% increase in age 0-19/20-39 years (chi-square = 223.10, p < .001). Number of cases over the initial analysis period were 0-19 years n = 515, 20-39 years n = 4078, 40-59 years n = 4788, 60-79 years n = 3221, 80+ years n = 1332. After the peak (March 22, 2020), incidence declined in older age groups and increased among age 0-19 and 20-39 age groups from 20% to 40% of total cases by April 19 and 50% by May 3. During this time testing expanded with more testing among older age groups and less testing among younger age groups while case positivity shifted young. Percent positive cases age 0-19/20-39 years through August 2020 increased to a consistent average of 60% [age 0-19 increased to 19% (N = 10257), age 20-39 increased to 42% (N = 30215)].
conclusionsAn increased sustained proportion of COVID-19 incidence is present among children (age 0-19) and young adults (age 20-39) indicating an elevated role in disease spread during the epidemic creating a possible reservoir of disease with spillover risk to more vulnerable older persons and those with comorbid conditions. Media savvy age-appropriate messaging to enhance mitigation compliance among less vulnerable, more mobile and lower priority vaccination age groups will be a continued necessity and priority to reduce overall population incidence.
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