Evidence map›Paper›PMID 33760701›Full record

ArticleAmerican journal of respiratory and critical care medicine2021

Inhibition of Caspase-1 with Tetracycline Ameliorates Acute Lung Injury.

Konrad Peukert, Mario Fox, Susanne Schulz, Caroline Feuerborn, Stilla Frede, Christian Putensen, Hermann Wrigge, Beate Mareike Kümmerer, Sascha David, Benjamin Seeliger and 6 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 92 citations in OpenAlex.

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    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 5 countries.

Konrad PeukertDepartment of Anesthesiology and Intensive Care Medicine.
Mario FoxDepartment of Anesthesiology and Intensive Care Medicine.
Susanne SchulzDepartment of Anesthesiology and Intensive Care Medicine.
Caroline FeuerbornDepartment of Anesthesiology and Intensive Care Medicine.
Stilla FredeDepartment of Anesthesiology and Intensive Care Medicine.
Christian PutensenDepartment of Anesthesiology and Intensive Care Medicine.
Hermann WriggeDepartment of Anesthesiology, Intensive Care and Emergency Medicine, Pain Therapy, Bergmannstrost Hospital Halle, Halle, Germany.
Beate Mareike KümmererInstitute of Virology.
Sascha DavidDepartment of Nephrology and Hypertension and.
Benjamin SeeligerDepartment of Respiratory Medicine and German Centre of Lung Research (DZL), Hannover Medical School, Hannover, Germany.
Tobias WelteDepartment of Respiratory Medicine and German Centre of Lung Research (DZL), Hannover Medical School, Hannover, Germany.
Eicke LatzInstitute of Innate Immunity, and.
Dennis KlinmanCancer and Inflammation Program, National Cancer Institute, Frederick, Maryland.
Christoph WilhelmInstitute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
Folkert SteinhagenDepartment of Anesthesiology and Intensive Care Medicine.
Christian BodeDepartment of Anesthesiology and Intensive Care Medicine.
Medizinische Hochschule Hannover · DEBG Klinikum Bergmannstrost Halle · DEInnate Pharma (France) · FRInstitute of Virology of the Slovak Academy of Sciences · SKNational Cancer Institute · USUniversity Hospital Bonn · DEUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute Lung InjuryAnimalsAnti-Bacterial AgentsCaspase 1Enzyme InhibitorsHumansImmunomodulationInflammasomesInterleukin-18Interleukin-1betaMiceModels, AnimalRespiratory Distress SyndromeTetracyclineAnti-Bacterial AgentsCaspase 1Enzyme InhibitorsInflammasomesInterleukin-18Interleukin-1betaTetracyclineantibacterial agentsimmunomodulationinflammasomesinfluenzaprecision medicine

Identifiers

PMID33760701
PMCPMC8437127
OpenAlexW3139448805

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.