Evidence map›Paper›PMID 33760131›Full record

ArticleMolecular medicine reports2021

Fine particulate matter induces airway inflammation by disturbing the balance between Th1/Th2 and regulation of GATA3 and Runx3 expression in BALB/c mice.

Lingling Pang, Pengfei Yu, Xueping Liu, Yingqi Fan, Ying Shi, Shenchun Zou

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Experimental and therapeutic medicine · 2025
    Article
  5. Particulate matter-induced epigenetic modifications and lung complications.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Expression levels ofAnnals of surgical treatment and research · 2023
    Article
  12. Article
  13. Recent Insights into Particulate Matter (PMInternational journal of environmental research and public health · 2022
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lingling Pang *Shandong University, Jinan, Shandong 250100, P.R. China.
Pengfei Yu *Shandong University, Jinan, Shandong 250100, P.R. China.
Xueping LiuDepartment of Respiratory Medicine, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.
Yingqi FanDepartment of Respiratory Medicine, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.
Ying ShiDepartment of Respiratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, P.R. China.
Shenchun ZouDepartment of Respiratory Medicine, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.
Yuhuangding Hospital · CNShandong University · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to examine the effects of 2.5 µm particulate matter (PM2.5) on airway inflammation and to investigate the possible underlying mechanism. Specifically, the focus was on the imbalance of T helper (Th)1/Th2 cells and the dysregulated expression of transcription factors, including

Indexed as

Air PollutantsAirway ObstructionAnimalsAsthmaCore Binding Factor Alpha 3 SubunitDisease Models, AnimalGATA3 Transcription FactorGene Expression RegulationHumansHypersensitivityMiceParticulate MatterSTAT6 Transcription FactorTh1 CellsTh1-Th2 BalanceTh2 CellsAir PollutantsCore Binding Factor Alpha 3 SubunitGata3 protein, mouseGATA3 Transcription FactorParticulate MatterRunx3 protein, mouseStat6 protein, mouseSTAT6 Transcription Factor2.5 µm particulate matterasthmarunt‑related transcription factor 3T helper 1/2trans‑acting T cell‑specific transcription factor GATA‑3

Identifiers

PMID33760131
PMCPMC7986036
OpenAlexW3136101658

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.