Evidence map›Paper›PMID 33760119›Full record

ArticleMolecular medicine reports2021

Exosomal microRNA-301a-3p promotes the proliferation and invasion of nasopharyngeal carcinoma cells by targeting BTG1 mRNA.

Qiang Cheng, Qiang Li, Lingen Xu, Hui Jiang

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
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  9. The roles ofFrontiers in genetics · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Qiang ChengDepartment of Otolaryngology, Jinshan Hospital Affiliated to Fudan University, Shanghai 201508, P.R. China.
Qiang LiDepartment of Otolaryngology, Jinshan Hospital Affiliated to Fudan University, Shanghai 201508, P.R. China.
Lingen XuDepartment of Otolaryngology, Jinshan Hospital Affiliated to Fudan University, Shanghai 201508, P.R. China.
Hui JiangDepartment of Otolaryngology, Jinshan Hospital Affiliated to Fudan University, Shanghai 201508, P.R. China.
Jinshan Hospital of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aberrant microRNA (miRNA/miR) expression plays an important role in the pathogenesis of nasopharyngeal carcinoma (NPC). In the present study, the role and underlying molecular mechanism of miR‑301a‑3p in NPC cells were determined. It was observed that miR‑301a‑3p upregulation promoted NPC cell proliferation, migration, invasion and epithelial‑mesenchymal transition

Indexed as

Cell Line, TumorCell MovementCell ProliferationEpithelial-Mesenchymal TransitionExosomesGene Expression Regulation, NeoplasticHumansMicroRNAsNasopharyngeal CarcinomaNeoplasm InvasivenessNeoplasm ProteinsRNA, MessengerBTG1 protein, humanMicroRNAsMIRN301A microRNA, humanNeoplasm ProteinsRNA, MessengerB-cell translocation gene 1invasionmicroRNA-301a-3pnasopharyngeal carcinomaproliferation

Identifiers

PMID33760119
PMCPMC7974331
OpenAlexW3135414706

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.