Evidence map›Paper›PMID 33759553›Full record

ArticleEnvironmental health perspectives2021

Contribution of Long-Term Exposure to Outdoor Black Carbon to the Carcinogenicity of Air Pollution: Evidence regarding Risk of Cancer in the Gazel Cohort.

Emeline Lequy, Jack Siemiatycki, Kees de Hoogh, Danielle Vienneau, Jean-François Dupuy, Valérie Garès, Ole Hertel, Jesper Heile Christensen, Sergey Zhivin, Marcel Goldberg and 2 more

Abstract read
In one paragraph

Article in Environmental health perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Impact of Pollution on Cancer: A Systematic Review and Meta-Analysis with Focus on Air Pollution.International journal of environmental research and public health · 2026
    Pooled it
  2. Pooled it
  3. Article
  4. Article
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  6. Black Carbon Air Pollution and Incident Mortality Among the Advance-Aged Adults in China: A Prospective Cohort Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Emeline LequyUMS 011, Institut national de la santé et de la recherché médicale (Inserm), Villejuif, France.
Jack SiemiatyckiCentre de recherche du centre hospitalier de l'université de Montréal, Université de Montréal, Québec, Canada.
Kees de HooghSwiss Tropical and Public Health Institute, Basel, Switzerland.
Danielle VienneauSwiss Tropical and Public Health Institute, Basel, Switzerland.
Jean-François DupuyUMR 6625 IRMAR, INSA, CNRS, Université de Rennes, Rennes, France.
Valérie GarèsUMR 6625 IRMAR, INSA, CNRS, Université de Rennes, Rennes, France.
Ole HertelDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Jesper Heile ChristensenDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Sergey ZhivinUMS 011, Institut national de la santé et de la recherché médicale (Inserm), Villejuif, France.
Marcel GoldbergUMS 011, Institut national de la santé et de la recherché médicale (Inserm), Villejuif, France.
Marie ZinsUMS 011, Institut national de la santé et de la recherché médicale (Inserm), Villejuif, France.
Bénédicte JacqueminUniv Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Rennes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlack carbon (BC), a component of fine particulate matter [particles with an aerodynamic diameter

objectiveThis study aimed to estimate the associations between long-term exposure to BC and risk of cancer. This study was conducted within the French Gazel cohort of 20,625 subjects.

methodsWe assessed exposure to BC by linking subjects' histories of residential addresses to a map of European black carbon levels in 2010 with back- and forward-extrapolation between 1989 and 2015. We used extended Cox models, with attained age as time-scale and time-varying cumulative exposure to BC, adjusted for relevant sociodemographic and lifestyle variables. To consider latency between exposure and cancer diagnosis, we implemented a 10-y lag, and as a sensitivity analysis, a lag of 2 y. To isolate the effect of BC from that of total

resultsDuring the 26-y follow-up period, there were 3,711 incident cancer cases (all sites combined) and 349 incident lung cancers. Median baseline exposure in 1989 was 2.65 DISCUSSION: Our findings for a cohort of French adults suggest that BC may partly explain the association between

Indexed as

Air PollutantsAir PollutionNeoplasmsAdultCarbonEnvironmental ExposureHumansParticulate MatterAir PollutantsCarbonParticulate Matter

Identifiers

PMID33759553
PMCPMC7989243

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.