Evidence map›Paper›PMID 33759238›Full record

ArticleMagnetic resonance in medicine2021

A theoretical framework for retrospective

Lexiaozi Fan, Bradley D Allen, Austin E Culver, Li-Yueh Hsu, Kyungpyo Hong, Brandon C Benefield, James C Carr, Daniel C Lee, Daniel Kim

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Myocardial blood flow quantification in patients with an implanted cardiodefibrillator during stress and at rest using a wideband perfusion pulse sequence: an initial feasibility study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Article
  3. A simplified method to correct saturation of arterial input function for cardiac magnetic resonance first-pass perfusion imaging: validation with simultaneously acquired PET.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lexiaozi FanDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0002-3714-5372
Bradley D AllenDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Austin E CulverDivision of Cardiology, Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Li-Yueh HsuDepartment of Radiology and Imaging Sciences, National Institutes of Health, Bethesda, Maryland, USA.
Kyungpyo HongDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0002-9453-6580
Brandon C BenefieldDivision of Cardiology, Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
James C CarrDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Daniel C LeeDivision of Cardiology, Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Daniel KimDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0003-2660-8973

Funding

Precision MRI of Left Atrial Fibrosis for Patients with Atrial FibrillationR01HL116895 · NHLBI · UNIVERSITY OF UTAH · PI KIM, DANIEL · 2014 to 2025
$5.1M
Wideband 3D LGE and Coronary MRA for Planning Ventricular Tachycardia AblationR01HL151079 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniel Kim, Daniel Ching-Hao Lee · 2020 to 2026
$4.0M
Rapid Real-Time Cardiovascular MRI for Detecting Coronary Artery DiseaseR01HL138578 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DANIEL, LEE, DANIEL CHING-HAO · 2017 to 2019
$1.1M
Rapid Pediatric Cardiovascular MRI without Contrast Agent or AnesthesiaR21EB024315 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DANIEL · 2017 to 2018
$567k
MRI of Left Atrial Hemodynamic Disorders in Atrial FibrillationR21AG055954 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DANIEL, MARKL, MICHAEL · 2017 to 2018
$487k
NHLBI NIH HHS R01 HL116895NHLBI NIH HHS R01 HL138578NHLBI NIH HHS R01 HL151079NIA NIH HHS R21 AG055954NIBIB NIH HHS R21 EB024315
6 · The paper itself

Abstract

purposeTo develop and evaluate a flexible, Bloch-equation based framework for retrospective

methodsOur framework initially calculates the gadolinium concentration [Gd] based on T

resultsCompared with the ground truth [Gd] of phantom, the normalized root-means-square-error (NRMSE) in measured [Gd] was 5.1%, 1.3%, and 0.6% for uncorrected, our corrected, and Kellman's corrected, respectively. For in vivo data, both the peak AIF (7.0 ± 3.0 mM vs. 8.6 ± 7.1 mM, 7.2 ± 0.9 mM vs. 8.6 ± 1.7 mM, 7.7 ± 1.8 mM vs. 10.3 ± 5.1 mM, P < .001) and resting MBF (1.3 ± 0.1 mL/g/min vs. 1.1 ± 0.1 mL/g/min, 1.3 ± 0.1 mL/g/min vs. 1.1 ± 0.1 mL/g/min, 1.2 ± 0.1 mL/g/min vs. 0.9 ± 0.1 mL/g/min, P < .001) values were significantly different between uncorrected and corrected for all 3 patient groups. Both the peak AIF and resting MBF values varied by <5% over the said variations in native T

conclusionOur theoretical framework enables retrospective

Indexed as

Contrast MediaMyocardial Perfusion ImagingCoronary CirculationHumansMagnetic Resonance ImagingPerfusionRetrospective StudiesContrast Mediaarterial input functionmyocardial blood flowperfusion

Identifiers

PMID33759238
PMCPMC8194096

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.