Evidence map›Paper›PMID 33759039›Full record

SynthesisNeuropsychology review2022

Apathy and Depression as Predictors of Activities of Daily Living Following Stroke and Traumatic Brain Injuries in Adults: A Meta-Analysis.

Sarah L Green, Gilles E Gignac, Prue A Watson, Nicky Brosnan, Rodrigo Becerra, Carmela Pestell, Michael Weinborn

Erratum issuedAbstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Neuropsychology review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Diminished Social and Leisure Engagement in Community Dwelling-Older Adults with Apathy.International journal of environmental research and public health · 2025
    Article
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  14. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sarah L GreenSchool of Psychology, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia, 6009, Australia.
Gilles E GignacSchool of Psychology, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia, 6009, Australia. gilles.gignac@uwa.edu.au.ORCID 0000-0002-4900-6855
Prue A WatsonSchool of Psychology, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia, 6009, Australia.
Nicky BrosnanSchool of Psychology, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia, 6009, Australia.
Rodrigo BecerraSchool of Psychology, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia, 6009, Australia.
Carmela PestellSchool of Psychology, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia, 6009, Australia.
Michael WeinbornSchool of Psychology, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia, 6009, Australia.
The University of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apathy and depression are common sequelae of acquired brain injury (ABI). Apathy is a syndrome characterized by diminished motivation and purposeful behaviours. Depression is a mood disorder featuring sadness, worthlessness, anhedonia and suicidal ideation. Both are associated negatively with activities of daily living (ADL), the skills required to fulfil basic and complex physical needs. However, the current literature's results are inconsistent and based on relatively small sample sizes. Furthermore, the unique and combined effects of apathy and depression as predictors of ADL have not yet been estimated. This is important, as both may have implications for planning rehabilitation after an ABI. Consequently, we aimed to estimate the association between apathy, depression and ADL in the stroke and traumatic brain injured population via meta-analysis and meta-analytic path-analysis. Based on the meta-analyses (N = 1,166 to N = 1,389), we estimated the following statistically significant bivariate effects: depression and apathy (r = .53, 95% CI: .42/.63), depression and ADL (r = -.27, 95% CI: -.43/-.11), apathy and ADL (r = -.41, 95% CI: -.51/-.31). A meta-analytic mediation model found that depression had a significant indirect effect onto ADL (β = -.17, 95% CI: -.26/-.09), while apathy had a significant direct effect (β = -.34, 95% CI: -.48/-.19) onto ADL (model R

Indexed as

ApathyBrain Injuries, TraumaticStrokeActivities of Daily LivingAdultDepressionHumansAcquired Brain InjuryActivities of Daily LivingApathyDepressionFunctional OutcomesStrokeTraumatic Brain Injury

Identifiers

PMID33759039
OpenAlexW3138572472

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.