ArticleProtoplasma2022
The ethylene-responsive transcription factor of durum wheat, TdSHN1, confers cadmium, copper, and zinc tolerance to yeast and transgenic tobacco plants.
Article in Protoplasma, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 44 citations in OpenAlex.
- Physiological and transcriptomic analyses reveal the critical role of MsERF15 in negatively regulating cadmium stress tolerance in Alfalfa (Medicago sativa).Journal of plant research · 2026Article
- Advances in Molecular Mechanisms Underlying Cadmium Accumulation and Detoxification in Durum Wheat (International journal of molecular sciences · 2026Review
- ChERF017, an ERF transcription factor, confers cadmium stress tolerance in Cerasus humilis.BMC plant biology · 2026Article
- Molecular Evolution of Cu Transporters and Transcription Factors in Plant Response to Copper Stress.Plants (Basel, Switzerland) · 2025Review
- Progress in Transcriptomics and Metabolomics in Plant Responses to Abiotic Stresses.Current issues in molecular biology · 2025Review
- Review
- Decoding the role of durum wheat ascorbate peroxidase TdAPX7B-2 in abiotic stress response.Functional & integrative genomics · 2024Article
- Genome-wide identification and analysis of ERF transcription factors related to abiotic stress responses in Nelumbo nucifera.BMC plant biology · 2024Article
- Metal transport proteins and transcription factor networks in plant responses to cadmium stress.Plant cell reports · 2024Review
- Synergistic interactions of assorted ameliorating agents to enhance the potential of heavy metal phytoremediation.Stress biology · 2024Review
- Transcription factors involved in plant responses to cadmium-induced oxidative stress.Frontiers in plant science · 2024Review
- The Effect of Cadmium on Plants in Terms of the Response of Gene Expression Level and Activity.Plants (Basel, Switzerland) · 2023Review
- Article
- Discovering Loci for Breeding Prospective and Phenology in Wheat Mediterranean Landraces by Environmental and eigenGWAS.International journal of molecular sciences · 2023Article
- Wheat Selenium-binding protein TaSBP-A enhances cadmium tolerance by decreasing free CdFrontiers in plant science · 2023Article
- Multi-Omics Uncover the Mechanism of Wheat under Heavy Metal Stress.International journal of molecular sciences · 2022Review
- Modifications of Phytohormone Metabolism Aimed at Stimulation of Plant Growth, Improving Their Productivity and Tolerance to Abiotic and Biotic Stress Factors.Plants (Basel, Switzerland) · 2022Review
- The Poplar (Plants (Basel, Switzerland) · 2022Article
- Transgenic tobacco co-expressing flavodoxin and betaine aldehyde dehydrogenase confers cadmium tolerance through boosting antioxidant capacity.Protoplasma · 2022Article
- Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Cadmium (Cd), copper (Cu), and zinc (Zn) are among the most common heavy metals (HMs) present in polluted soils. While some HMs are required for key biological processes, they are toxic when present in excess. This toxicity damages plant health, decreases crop yields, and can impact human health via the food chain. For example, durum wheat is a staple food that is known to accumulate Cd when grown on polluted soils. Plant response to HM stress is complex and involves several transcription factors (TFs) among which members of the ERF family. Although roles of SHINE-type ERF transcription factors in abiotic stress tolerance have been thoroughly investigated, there is little information concerning their role in HM stress tolerance. In the present study, we investigated the role of durum wheat TdSHN1 TF in HM response and tolerance. Results showed that TdSHN1 expression was strongly induced by Cd, Cu, and Zn in durum wheat seedlings. In addition, TdSHN1 gene promoter directed HM-inducible GUS gene expression in transgenic tobacco. Overexpression of TdSHN1 encoding cDNA in transgenic yeast and tobacco conferred Cd, Cu, and Zn tolerances. Interestingly, transgenic tobacco lines exhibited longer roots and greater biomass accumulation, retained more chlorophyll, and produced less ROS than WT plants, when subjected to excess HMs. In addition, transgenic tobacco lines had higher activities of ROS-scavenging enzymes (SOD and CAT) which might have contributed to their HM tolerance. This study suggested that TdSHN1 is a potential candidate for improving HM tolerance in plants and phytoremediation of HM-contaminated soils.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.