Evidence map›Paper›PMID 33759012›Full record

SynthesisActa neurochirurgica2021

Complications of cranioplasty following decompressive craniectomy for traumatic brain injury: systematic review and meta-analysis.

Jack Henry, Michael Amoo, Adam Murphy, David P O'Brien

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Acta neurochirurgica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06740773 (A Retrospective Study to Identify Risk Factors for Complications After Cranioplasty), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06740773 recruitingnot on this mapstarted 2024, after this paper: background citation

A Retrospective Study to Identify Risk Factors for Complications After Cranioplasty

TypeobservationalSponsorQilu Hospital of Shandong UniversityRan2024 to 2025Enrolled1,000ConditionsCranioplasty, Postoperative Complications, Risk Assessment
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

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  17. [Application of two-stage operation on free latissimus dorsi myocutaneous flap transplantation and skull contour reconstruction in treatment of head titanium mesh exposure with soft tissue infection].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jack HenryNational Centre for Neurosurgery, Beaumont Hospital, Dublin, Ireland. jack.henry@ucdconnect.ie.ORCID 0000-0001-5662-198X
Michael AmooNational Centre for Neurosurgery, Beaumont Hospital, Dublin, Ireland.
Adam MurphyNational Centre for Neurosurgery, Beaumont Hospital, Dublin, Ireland.
David P O'BrienNational Centre for Neurosurgery, Beaumont Hospital, Dublin, Ireland.
Beaumont Hospital · IERoyal College of Surgeons in Ireland · IEUniversity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDecompressive craniectomy (DC) is a common neurosurgical intervention for severe traumatic brain injury (TBI), as well as malignant stroke, malignancy and infection. DC necessitates subsequent cranioplasty. There are significant demographic differences between TBI and non-TBI patients undergoing cranioplasty, which may influence their relative risk profiles for infection, aseptic bone flap resorption (aBFR) and re-operation.

objectivePerform a meta-analysis to determine the relative infection, aBFR and re-operation risk profiles of TBI patients as compared to other indications for DC.

methodsA systematic review and meta-analysis was performed in accordance with the PRISMA guidelines. PubMed, MEDLINE, EMBASE and Google Scholar were searched until 26/11/2020. Studies detailing rates of infection, re-operation and/or aBFR in specific materials and the post-TBI population were included, while studies in paediatrics or craniosynostosis repair were excluded.

resultsTwenty-six studies were included. There was no difference in relative risk of infection between TBI and non-TBI cohorts (RR 0.81, 95% CI 0.57-1.17), with insignificant heterogeneity (I

conclusionTBI is a risk factor for aBFR and re-operation following cranioplasty. Use of an alloplastic graft for primary cranioplasty in these patients may partially mitigate this increased risk.

Indexed as

Brain Injuries, TraumaticDecompressive CraniectomyHumansPostoperative ComplicationsReoperationAseptic bone flap resorptionCranioplastyDecompressive craniectomyTraumatic brain injury

Identifiers

PMID33759012
OpenAlexW3138592422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.