Evidence map›Paper›PMID 33758994›Full record

ReviewCurrent gastroenterology reports2021

Luminal Gastrointestinal Manifestations of Cystic Fibrosis.

Samuel J Burton, Christine Hachem, James M Abraham

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Investigating the Association Between Cystic Fibrosis and Colorectal Neoplasia: A Matched Case-Control Study.JGH open : an open access journal of gastroenterology and hepatology · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. A new era for people with cystic fibrosis.European journal of pediatrics · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Samuel J BurtonDivision of Gastroenterology and Hepatology, Saint Louis University, St. Louis, MI, USA.ORCID http://orcid.org/0000-0003-1903-588X
Christine HachemDivision of Gastroenterology and Hepatology, Saint Louis University, St. Louis, MI, USA.
James M AbrahamDepartment of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA. jamabrah@med.umich.edu.
Saint Louis University · USUniversity of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewPeople with cystic fibrosis (CF) are living longer. General age-related and CF-specific gastrointestinal symptoms are increasingly recognized. In this article, we review the latest data on luminal gastrointestinal manifestations in CF. RECENT

findingsPeople with CF have increased incidence of gastroesophageal reflux disease symptoms and often prescribed proton-pump inhibitors (PPI). PPI use may increase risk of pulmonary exacerbations. Evidence to support gastric fundoplication to improve pulmonary outcomes is limited. Features of intestinal dysmotility are common. There are distinct differences in the gut microbiome in the CF population which may have clinical implications. CF is a possible hereditary digestive cancer syndrome, particularly in regard to colorectal cancer (CRC) with earlier incidence of CRC and advanced colonic neoplasia. Early screening colonoscopy is warranted in the CF population. Gastrointestinal manifestations in CF are prevalent across all digestive organs. More study on the effect of interventions for symptomatic treatment and cancer screening is needed.

Indexed as

Colonic NeoplasmsCystic FibrosisColonoscopyEarly Detection of CancerFundoplicationHumansColorectal cancerCystic fibrosisDysmotilityGERDLung transplant

Identifiers

PMID33758994
OpenAlexW3136371037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.