Evidence map›Paper›PMID 33758903›Full record

ArticlemedRxiv : the preprint server for health sciences2021

Exposure to SARS-CoV-2 within the household is associated with greater symptom severity and stronger antibody responses in a community-based sample of seropositive adults.

Joshua M Schrock, Daniel T Ryan, Rana Saber, Nanette Benbow, Lauren A Vaught, Nina Reiser, Matthew P Velez, Ryan Hsieh, Michael Newcomb, Alexis R Demonbreun and 4 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Joshua M SchrockInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University.
Daniel T RyanInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University.
Rana SaberInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University.
Nanette BenbowDepartment of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine.
Lauren A VaughtCenter for Genetic Medicine, Northwestern University.
Nina ReiserCenter for Genetic Medicine, Northwestern University.
Matthew P VelezCenter for Genetic Medicine, Northwestern University.
Ryan HsiehCenter for Genetic Medicine, Northwestern University.
Michael NewcombInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University.
Alexis R DemonbreunCenter for Genetic Medicine, Northwestern University.
Brian MustanskiInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University.
Elizabeth M McNallyCenter for Genetic Medicine, Northwestern University.
Richard D'AquilaDivision of Infectious Diseases, Dept. of Medicine, Northwestern University Feinberg School of Medicine.
Thomas W McDadeDepartment of Anthropology, Northwestern University.
Northwestern University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
NCATS NIH HHS UL1 TR001422
6 · The paper itself

Abstract

Magnitude of SARS-CoV-2 virus exposure may contribute to symptom severity. In a sample of seropositive adults (n=1101), we found that individuals who lived with a known COVID-19 case exhibited greater symptom severity and IgG concentrations compared to individuals who were seropositive but did not live with a known case (P<0.0001).

Identifiers

PMID33758903
PMCPMC7987062
OpenAlexW3139152755

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.