Evidence map›Paper›PMID 33758804›Full record

ArticleArchives of rheumatology2020

Association Between Familial Mediterranean Fever and Cachexia in Females.

Yunus Durmaz, İlker Ilhanli, Ahmet Kıvanç Cengiz, Ece Kaptanoğlu, Zekiye Özkan Hasbek, Sami Hizmetli

Open access · diamondAbstract read
In one paragraph

Article in Archives of rheumatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Yunus DurmazDepartment of Physical Medicine and Rehabilitation, Division of Rheumatology, Karabük Training and Research Hospital, Karabük, Turkey.ORCID 0000-0002-1727-0088
İlker IlhanliDepartment of Physical Medicine and Rehabilitation, Division of Rheumatology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey.ORCID 0000-0002-7998-8992
Ahmet Kıvanç CengizDepartment of Physical Medicine and Rehabilitation, Division of Rheumatology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey.ORCID 0000-0002-4390-7169
Ece KaptanoğluDepartment of Physical Medicine and Rehabilitation, Division of Rheumatology, Başkent University Zübeyde Hanım Application and Research Center, İzmir, Turkey.ORCID 0000-0001-8580-3635
Zekiye Özkan HasbekDepartment ofNuclear Medicine, Cumhuriyet University Faculty of Medicine, Sivas, Turkey.ORCID 0000-0002-8119-3363
Sami HizmetliDepartment of Physical Medicine and Rehabilitation, Division of Rheumatology, Cumhuriyet University Faculty of Medicine, Sivas, Turkey.ORCID 0000-0002-0418-0155
Ondokuz Mayıs University · TRSivas Cumhuriyet Üniversitesi · TRBaşkent University · TRKarabük University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aims to investigate the association between familial Mediterranean fever (FMF) and cachexia in females. PATIENTS AND

methodsThe study included 32 female FMF patients (median age 27.50 years; range, 18 to 50 years) and 30 female healthy controls (median age 32 years; range, 18 to 50 years). Patients were classified according to Tel-Hashomer criteria. Circumference of arm, waist, and thigh was recorded. Short form 36 (SF-36) and Multidimensional Assessment of Fatigue (MAF) scale were applied. Composition of the body was measured with dual X-ray absorption. Muscle strength was measured with an isokinetic dynamometer, and strength of hand grip was measured from dominant hand with a hand dynamometer. C-reactive protein, erythrocyte sedimentation rate, fibrinogen and serum creatinine kinase (CK) levels were recorded.

resultsBody mass index was significantly higher in controls. Twelve patients and one control had cachexia. CK level was significantly higher in patients than controls. Mass of muscle without fat was significantly higher in patients than controls. Peak torque values of extension and flexion at the velocity of 60°/second [Newton meter (Nm)], and value of total work during extension at the velocity of 240°/second (Nm) in isokinetic measures were significantly higher in controls. MAF score was significantly higher in patients with cachexia than patients without cachexia where the subscale scores of SF-36, except the vitality score, were significantly lower in patients with cachexia. However, Tel-Hashomer score was significantly higher in patients with cachexia.

conclusionThis study pointed at a significant association between cachexia and FMF in females. Muscle endurance was not affected in FMF patients with cachexia; however, decreased muscle strength, impaired quality of life and increased fatigue were observed in these patients.

Identifiers

PMID33758804
PMCPMC7945703
OpenAlexW3112067324

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.