ArticleJournal of perinatology : official journal of the California Perinatal Association2021
Vasoactive medications in extremely low gestational age neonates during the first postnatal week.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Outcomes of extremely preterm infants who participated in a randomised trial of dopamine for treatment of hypotension (the HIP trial) at 2 years corrected age.Archives of disease in childhood. Fetal and neonatal edition · 2025Trial
- Neonatal Postresuscitation Care in Brazil: A National Overview.American journal of perinatology · 2026Article
- Clinical risk factors predicting likelihood of pathogenic genetic result in NICU patients.Genetics in medicine open · 2026Article
- Strong Association between Inotrope Administration and Intraventricular Hemorrhage, Gestational Age, and the Use of Fentanyl in Very Low Gestational Age Infants: A Retrospective Study.Children (Basel, Switzerland) · 2023Article
- Use of vasopressors for septic shock in the neonatal intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2023Article
- Impact of Early Hemodynamic Screening on Extremely Preterm Outcomes in a High-Performance Center.American journal of respiratory and critical care medicine · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
objectiveThe management of early hypotension in extremely low gestational age neonates (ELGANs) varies greatly between centers. The objective of this study was to provide updated data on the use of vasoactive medications in ELGANs during the first postnatal week. STUDY
designWe identified ELGANs (22-27 weeks gestational age) cared for at Pediatrix neonatal intensive care units from 2009 to 2018. We evaluated the frequency of exposure to vasoactive medications by gestational age, and compared use of vasoactive medications between two epochs (2009-2013 and 2014-2018).
resultsA total of 10,070/34,234 (29%) ELGANs received ≥1 vasoactive medication. Dopamine was the most frequently used vasoactive medication. The majority (83%) of treated ELGANs initiated therapy on postnatal days 0-1. Overall use of vasoactive medications was slightly lower in 2014-2018 than 2009-2013 (28 vs 31%, p < 0.001).
conclusionA substantial proportion of ELGANs were exposed to vasoactive medications during the first postnatal week.
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Registered trials
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