ArticleCommunications biology2021
Boundary conditions investigation to improve computer simulation of cerebrospinal fluid dynamics in hydrocephalus patients.
Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 62 citations in OpenAlex.
- Digital Twins as the Implementation Layer of Precision Medicine in Pediatric Neurosurgery.Journal of Korean Neurosurgical Society · 2026Review
- Catheter architecture as a determinant of cerebrospinal fluid flow in pediatric hydrocephalus.Fluids and barriers of the CNS · 2026Article
- Role of cerebroventricular size and surgical placement in modulating catheter flow distribution.Fluids and barriers of the CNS · 2026Article
- Smart Nanomedicines for Neurodegenerative Diseases: Empowering New Therapies with Molecular Imaging and Artificial Intelligence.Molecular diagnosis & therapy · 2026Review
- Mixed-dimensional fluid-structure interaction simulations reveal key mechanisms of cerebrospinal fluid dynamics in the spinal canal.Fluids and barriers of the CNS · 2025Article
- Fluid dynamics model of the cerebral ventricular system.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Insights into the Role of the Glymphatic System in the Pathogenesis of Post-hemorrhagic Hydrocephalus.Molecular neurobiology · 2025Review
- Super-Resolving and Denoising 4D flow MRI of Neurofluids Using Physics-Guided Neural Networks.Annals of biomedical engineering · 2025Article
- Feasibility of assessing non-invasive intracranial compliance using FSI simulation-based and MR elastography-based brain stiffness.Scientific reports · 2024Article
- Optimization of number and range of shunt valve performance levels in infant hydrocephalus: a machine learning analysis.Frontiers in bioengineering and biotechnology · 2024Article
- Computational Fluid Dynamics of Cerebrospinal Fluid.Advances in experimental medicine and biology · 2024Review
- Impact of thermodynamical rotational flow of cerebrospinal fluid in the presence of elasticity.BMC research notes · 2023Article
- Why Intracranial Compliance Is Not Utilized as a Common Practical Tool in Clinical Practice.Biomedicines · 2023Review
- Neural simulation pipeline: Enabling container-based simulations on-premise and in public clouds.Frontiers in neuroinformatics · 2023Article
- Editorial: Modeling and simulation of cerebrospinal fluid disorders.Frontiers in bioengineering and biotechnology · 2023Article
- Long-term recovery behavior of brain tissue in hydrocephalus patients after shunting.Communications biology · 2022Article
- A one-dimensional model for the pulsating flow of cerebrospinal fluid in the spinal canal.Journal of fluid mechanics · 2022Article
- Computational fluid dynamics model to predict the dynamical behavior of the cerebrospinal fluid through implementation of physiological boundary conditions.Frontiers in bioengineering and biotechnology · 2022Article
- A Clinical Study on the Treatment of Recurrent Chiari (Type I) Malformation with Syringomyelia Based on the Dynamics of Cerebrospinal Fluid.BioMed research international · 2022Article
- A New Definition for Intracranial Compliance to Evaluate Adult Hydrocephalus After Shunting.Frontiers in bioengineering and biotechnology · 2022Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Three-D head geometrical models of eight healthy subjects and 11 hydrocephalus patients were built using their CINE phase-contrast MRI data and used for computer simulations under three different inlet/outlet boundary conditions (BCs). The maximum cerebrospinal fluid (CSF) pressure and the ventricular system volume were more effective and accurate than the other parameters in evaluating the patients' conditions. In constant CSF pressure, the computational patient models were 18.5% more sensitive to CSF volume changes in the ventricular system under BC "C". Pulsatile CSF flow rate diagrams were used for inlet and outlet BCs of BC "C". BC "C" was suggested to evaluate the intracranial compliance of the hydrocephalus patients. The results suggested using the computational fluid dynamic (CFD) method and the fully coupled fluid-structure interaction (FSI) method for the CSF dynamic analysis in patients with external and internal hydrocephalus, respectively.
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