SynthesisScientific reports2021
Comparison of trifocal or hybrid multifocal-extended depth of focus intraocular lenses: a systematic review and meta-analysis.
Synthesis in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Visual Outcomes After Mix-and-Match Implantation of Trifocal and Extended Depth-of-Focus Intraocular Lenses: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Trifocal versus extended depth of focus (EDOF) intraocular lenses after cataract extraction.The Cochrane database of systematic reviews · 2024Pooled it
- Presbyopia-Correcting Intraocular Lenses Implantation in Eyes After Corneal Refractive Laser Surgery: A Meta-Analysis and Systematic Review.Frontiers in medicine · 2022Pooled it
- Visual, clinical and quality of life outcomes of a new multifocal IOL with optimized diffractive grating: a non-randomized clinical trial.BMC ophthalmology · 2025Trial
- Clinical Outcomes of a Bi-Aspheric Trifocal Diffractive Intraocular Lens.Clinical ophthalmology (Auckland, N.Z.) · 2024Trial
- Comparison of bilateral implantation of an extended depth of focus lenses and a blend approach of extended depth of focus lenses and bifocal lenses in cataract patients.BMC ophthalmology · 2023Trial
- Diffractive intraocular lenses reshape 577-nm retinal laser photocoagulation spots in a model eye.Lasers in medical science · 2026Article
- Visual performance of a non-diffractive extended depth of focus IOL in stable early-stage Keratoconus: prospective pilot study.International ophthalmology · 2026Article
- Advances in cataract surgery: is a new era on the horizon?Current opinion in ophthalmology · 2026Review
- Halo Measurements in Simulated Multifocal Intraocular Lenses.Translational vision science & technology · 2026Article
- Objective assessment of accommodation with an accommodative intraocular lens: Development of methodology and case report.Zeitschrift fur medizinische Physik · 2026Article
- Comparison of visual performance outcomes following PanOptix and symfony ZXR00 intraocular lens implantation using the area under the distance-corrected defocus curve.BMC ophthalmology · 2026Article
- Higher-order aberrations and visual outcomes of a new refractive extended depth-of-focus intraocular lens with a target of slight myopia.Scientific reports · 2026Article
- Factors Affecting Postoperative Satisfaction After Presbyopia-Correcting Intraocular Lens.Journal of clinical medicine · 2026Review
- Early Clinical Outcomes After the Mix-and-Match Approach of Trifocal and Non-Diffractive EDOF IOL.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Comparison of visual outcomes between bilateral EDOF IOL implantation and combined EDOF and bifocal IOL implantation.International journal of ophthalmology · 2026Article
- A One-Year Visual and Safety Evaluation of a Newly Available Trifocal Intraocular Lens in Patients With Bilateral Cataracts: Clinical Outcomes From a Prospective Study.Journal of ophthalmology · 2026Article
- Comparison of Visual Performance and Patient Satisfaction Between Two Trifocal Intraocular Lenses: A Prospective, Paired-Eye Comparative Study.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- A Retrospective Study: Comparative Visual Performance of Two Non-Diffractive Extended Depth-of-Focus Intraocular Lenses: TECNIS PureSee versus Clareon Vivity.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Distance Visual Outcomes of Trifocal Intraocular Lenses in Highly Myopic Eyes Without Myopic Maculopathy.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This meta-analysis aimed to evaluate the clinical outcomes following implantation of trifocal intraocular lenses (IOLs) or a hybrid multifocal-extended depth of focus (EDOF) IOL in cataract or refractive lens exchange surgeries. We examined 13 comparative studies with bilateral implantation of trifocal (898 eyes) or hybrid multifocal-EDOF (624 eyes) IOLs published through 1 March 2020. Better uncorrected and corrected near visual acuity (VA) were observed in the trifocal group (MD: - 0.143, 95% CI: - 0.192 to - 0.010, P < 0.001 and MD: - 0.149, 95% CI: - 0.217 to - 0.082, P < 0.001, respectively), while the hybrid multifocal-EDOF group presented better uncorrected intermediate VA (MD: 0.055, 95% CI: 0.016 to 0.093, P = 0.005). Trifocal IOLs were more likely to achieve spectacle independence at near distance (RR: 1.103, 95% CI: 1.036 to 1.152, P = 0.002). The halo photic effect was generated more frequently by the trifocal IOLs (RR: 1.318, 95% CI: 1.025 to 1.696, P = 0.031). Contrast sensitivity and subjective visual quality yielded comparable results between groups. Trifocal IOLs demonstrated better performance at near distance but apparently led to more photic disturbances. Our findings provided the most up-to-date and comprehensive evidence by comparing the benefits of advanced IOLs in clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.