Evidence map›Paper›PMID 33758277›Full record

ArticleScientific reports2021

Origin and diffusion of human Y chromosome haplogroup J1-M267.

Hovhannes Sahakyan, Ashot Margaryan, Lauri Saag, Monika Karmin, Rodrigo Flores, Marc Haber, Alena Kushniarevich, Zaruhi Khachatryan, Ardeshir Bahmanimehr, Jüri Parik and 12 more

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Metagenomic peek into a corn mummy.Scientific reports · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Hovhannes Sahakyan *Estonian Biocentre, Institute of Genomics, University of Tartu, 51010, Tartu, Estonia. hovhannes.sahakyan@ut.ee.
Ashot Margaryan *Laboratory of Evolutionary Genomics, Institute of Molecular Biology of National Academy of Sciences of the Republic of Armenia, 0014, Yerevan, Armenia.
Lauri SaagEstonian Biocentre, Institute of Genomics, University of Tartu, 51010, Tartu, Estonia.
Monika KarminEstonian Biocentre, Institute of Genomics, University of Tartu, 51010, Tartu, Estonia.
Rodrigo FloresEstonian Biocentre, Institute of Genomics, University of Tartu, 51010, Tartu, Estonia.
Marc HaberInstitute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
Alena KushniarevichEstonian Biocentre, Institute of Genomics, University of Tartu, 51010, Tartu, Estonia.
Zaruhi KhachatryanLaboratory of Evolutionary Genomics, Institute of Molecular Biology of National Academy of Sciences of the Republic of Armenia, 0014, Yerevan, Armenia.
Ardeshir BahmanimehrLaboratory of Evolutionary Genomics, Institute of Molecular Biology of National Academy of Sciences of the Republic of Armenia, 0014, Yerevan, Armenia.
Jüri ParikEstonian Biocentre, Institute of Genomics, University of Tartu, 51010, Tartu, Estonia.
Tatiana KarafetARL Division of Biotechnology, University of Arizona, Tucson, AZ, 85721, USA.
Bayazit YunusbayevEstonian Biocentre, Institute of Genomics, University of Tartu, 51010, Tartu, Estonia.
Tuuli ReisbergCore Facility, Institute of Genomics, University of Tartu, 51010, Tartu, Estonia.
Anu SolnikEstonian Biocentre, Institute of Genomics, University of Tartu, 51010, Tartu, Estonia.
Ene MetspaluEstonian Biocentre, Institute of Genomics, University of Tartu, 51010, Tartu, Estonia.
Anahit HovhannisyanLaboratory of Evolutionary Genomics, Institute of Molecular Biology of National Academy of Sciences of the Republic of Armenia, 0014, Yerevan, Armenia.
Elza K KhusnutdinovaDepartment of Genetics and Fundamental Medicine of Bashkir State University, Ufa, Bashkortostan, Russia, 450076.
Doron M BeharEstonian Biocentre, Institute of Genomics, University of Tartu, 51010, Tartu, Estonia.
Mait MetspaluEstonian Biocentre, Institute of Genomics, University of Tartu, 51010, Tartu, Estonia.
Levon YepiskoposyanLaboratory of Evolutionary Genomics, Institute of Molecular Biology of National Academy of Sciences of the Republic of Armenia, 0014, Yerevan, Armenia.
Siiri Rootsi *Estonian Biocentre, Institute of Genomics, University of Tartu, 51010, Tartu, Estonia.
Richard Villems *Estonian Biocentre, Institute of Genomics, University of Tartu, 51010, Tartu, Estonia.

Funding

New York Center for Collaborative Research In Common Disease Genomics: Genome Aggregation and Joint Variant Calling for CCDG Freeze2UM1HG008901 · NHGRI · NEW YORK GENOME CENTER · PI MANIATIS, THOMAS P, WIGLER, MICHAEL H · 2016 to 2020
$56.6M
NHGRI NIH HHS UM1 HG008901
6 · The paper itself

Abstract

Human Y chromosome haplogroup J1-M267 is a common male lineage in West Asia. One high-frequency region-encompassing the Arabian Peninsula, southern Mesopotamia, and the southern Levant-resides ~ 2000 km away from the other one found in the Caucasus. The region between them, although has a lower frequency, nevertheless demonstrates high genetic diversity. Studies associate this haplogroup with the spread of farming from the Fertile Crescent to Europe, the spread of mobile pastoralism in the desert regions of the Arabian Peninsula, the history of the Jews, and the spread of Islam. Here, we study past human male demography in West Asia with 172 high-coverage whole Y chromosome sequences and 889 genotyped samples of haplogroup J1-M267. We show that this haplogroup evolved ~ 20,000 years ago somewhere in northwestern Iran, the Caucasus, the Armenian Highland, and northern Mesopotamia. The major branch-J1a1a1-P58-evolved during the early Holocene ~ 9500 years ago somewhere in the Arabian Peninsula, the Levant, and southern Mesopotamia. Haplogroup J1-M267 expanded during the Chalcolithic, the Bronze Age, and the Iron Age. Most probably, the spread of Afro-Asiatic languages, the spread of mobile pastoralism in the arid zones, or both of these events together explain the distribution of haplogroup J1-M267 we see today in the southern regions of West Asia.

Indexed as

AllelesChromosomes, Human, YHaplotypesBayes TheoremEvolution, MolecularGenetics, PopulationHumansPhylogenyPolymorphism, Single NucleotideSpatio-Temporal Analysis

Identifiers

PMID33758277
PMCPMC7987999

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.