ArticleScientific reports2021
Computational characterization of inhaled droplet transport to the nasopharynx.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
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- A Modular Mathematical Model of the Immune Response for Investigating the Pathogenesis of Infectious Diseases.Viruses · 2025Article
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- Mechanics-guided parametric modeling of intranasal spray devices and formulations for targeted drug delivery to the nasopharynx.Frontiers in drug delivery · 2025Article
- Perspectives on physics-based one-dimensional modeling of lung physiology.Frontiers in physiology · 2025Article
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- Insights into the fluid dynamics of bioaerosol formation in a model respiratory tract.Biomicrofluidics · 2024Article
- Simplified models of aerosol collision and deposition for disease transmission.Scientific reports · 2023Article
- Development of a multiphase perfusion model for biomimetic reduced-order dense tumors.Experimental and computational multiphase flow · 2023Article
- Visualization and Estimation of Nasal Spray Delivery to Olfactory Mucosa in an Image-Based Transparent Nasal Model.Pharmaceutics · 2023Article
- A Negative-Pressure Face-Mounted System Reduces Aerosol Spread during Endonasal Endoscopic Surgery.Journal of neurological surgery. Part B, Skull base · 2023Article
- Hybrid discrete-time-continuous-time models and a SARS CoV-2 mystery: Sub-Saharan Africa's low SARS CoV-2 disease burden.Journal of mathematical biology · 2023Article
- Impact of supplementary air filtration on aerosols and particulate matter in a UK hospital ward: a case study.The Journal of hospital infection · 2023Article
- Risk assessment of banknotes as a fomite of SARS-CoV-2 in cash payment transactions.Risk analysis : an official publication of the Society for Risk Analysis · 2023Article
- How much natural ventilation rate can suppress COVID-19 transmission in occupancy zones?Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2023Article
- Inhalation of virus-loaded droplets as a clinically plausible pathway to deep lung infection.Frontiers in physiology · 2023Article
- Compellingly high SARS-CoV-2 susceptibility of Golden Syrian hamsters suggests multiple zoonotic infections of pet hamsters during the COVID-19 pandemic.Scientific reports · 2022Article
- Detection of SARS-CoV-2 in the air in Indian hospitals and houses of COVID-19 patients.Journal of aerosol science · 2022Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
How human respiratory physiology and the transport phenomena associated with inhaled airflow in the upper airway proceed to impact transmission of SARS-CoV-2, leading to the initial infection, stays an open question. An answer can help determine the susceptibility of an individual on exposure to a COVID-2019 carrier and can also provide a preliminary projection of the still-unknown infectious dose for the disease. Computational fluid mechanics enabled tracking of respiratory transport in medical imaging-based anatomic domains shows that the regional deposition of virus-laden inhaled droplets at the initial nasopharyngeal infection site peaks for the droplet size range of approximately 2.5-19 [Formula: see text]. Through integrating the numerical findings on inhaled transmission with sputum assessment data from hospitalized COVID-19 patients and earlier measurements of ejecta size distribution generated during regular speech, this study further reveals that the number of virions that may go on to establish the SARS-CoV-2 infection in a subject could merely be in the order of hundreds.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.