Evidence map›Paper›PMID 33758164›Full record

ArticleSignal transduction and targeted therapy2021

The lncRNA Snhg1-Vps13D vesicle trafficking system promotes memory CD8 T cell establishment via regulating the dual effects of IL-7 signaling.

Yanyan Zhang, Baohua Li, Qiang Bai, Pengcheng Wang, Gang Wei, Zhirong Li, Li Hu, Qin Tian, Jing Zhou, Qizhao Huang and 9 more

Open access · goldAbstract read
In one paragraph

Article in Signal transduction and targeted therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 49 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Exercise and CD8Journal of molecular medicine (Berlin, Germany) · 2026
    Review
  7. Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Advances in IL-7 Research on Tumour Therapy.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. The Role of IL-7 and IL-7R in Cancer Pathophysiology and Immunotherapy.International journal of molecular sciences · 2022
    Review
  20. (Epi)transcriptomics in cardiovascular and neurological complications of COVID-19.Journal of molecular and cellular cardiology plus · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 3 countries.

Yanyan Zhang *Institute of Immunology PLA, Third Military Medical University, Chongqing, 400038, China. yzhangtmmu@163.com.ORCID 0000-0002-6037-5918
Baohua Li *Institute of Immunology PLA, Third Military Medical University, Chongqing, 400038, China.
Qiang Bai *Institute of Immunology PLA, Third Military Medical University, Chongqing, 400038, China.ORCID 0000-0001-7423-0712
Pengcheng WangInstitute of Immunology PLA, Third Military Medical University, Chongqing, 400038, China.
Gang WeiHuman Phenome Institute, Fudan University, Shanghai, 200438, China.
Zhirong LiInstitute of Immunology PLA, Third Military Medical University, Chongqing, 400038, China.
Li HuInstitute of Immunology PLA, Third Military Medical University, Chongqing, 400038, China.
Qin TianInstitute of Immunology PLA, Third Military Medical University, Chongqing, 400038, China.
Jing ZhouInstitute of Immunology PLA, Third Military Medical University, Chongqing, 400038, China.
Qizhao HuangInstitute of Immunology PLA, Third Military Medical University, Chongqing, 400038, China.
Zhiming WangInstitute of Immunology PLA, Third Military Medical University, Chongqing, 400038, China.
Shuai YueInstitute of Immunology PLA, Third Military Medical University, Chongqing, 400038, China.
Jialin WuInstitute of Immunology PLA, Third Military Medical University, Chongqing, 400038, China.
Liuqing YangDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, 77030, TX, USA.ORCID 0000-0002-6518-474X
Xinyuan ZhouInstitute of Immunology PLA, Third Military Medical University, Chongqing, 400038, China.
Lubin JiangInstitute Pasteur of Shanghai, Chinese Academy of Sciences (CAS), Shanghai, 200031, China.
Ting NiHuman Phenome Institute, Fudan University, Shanghai, 200438, China.
Lilin YeInstitute of Immunology PLA, Third Military Medical University, Chongqing, 400038, China. yelilinlcmv@tmmu.edu.cn.ORCID 0000-0003-0778-3311
Yuzhang WuInstitute of Immunology PLA, Third Military Medical University, Chongqing, 400038, China. wuyuzhang@tmmu.edu.cn.
Army Medical University · CNFudan University · CNChinese Academy of Sciences · CNThe University of Texas MD Anderson Cancer Center · US

Funding

National Natural Science Foundation of China (National Science Foundation of China) 2016YFA0502202National Natural Science Foundation of China (National Science Foundation of China) 31800763
6 · The paper itself

Abstract

The efficient induction and long-term persistence of pathogen-specific memory CD8 T cells are pivotal to rapidly curb the reinfection. Recent studies indicated that long-noncoding RNAs expression is highly cell- and stage-specific during T cell development and differentiation, suggesting their potential roles in T cell programs. However, the key lncRNAs playing crucial roles in memory CD8 T cell establishment remain to be clarified. Through CD8 T cell subsets profiling of lncRNAs, this study found a key lncRNA-Snhg1 with the conserved naive

Indexed as

AnimalsBiological Transport, ActiveCD8-Positive T-LymphocytesCOVID-19HumansImmunologic MemoryInterleukin-7MiceProteinsRNA, Long NoncodingSARS-CoV-2Secretory VesiclesSignal TransductionIL7 protein, humanInterleukin-7long non-coding RNA SNHG1, humanProteinsRNA, Long NoncodingVPS13D protein, human

Identifiers

PMID33758164
PMCPMC7987995
OpenAlexW3138960484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.