Evidence map›Paper›PMID 33758106›Full record

ArticleAging2021

Development and validation of a RNA binding protein-associated prognostic model for head and neck squamous cell carcinoma.

Xiuping Yang, Baoai Han, Runshi Zhang, Yuan Su, Davood K Hosseini, Han Wu, Minlan Yang, Haiying Sun

Open access · greenAbstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Xiuping YangDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Baoai HanDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Runshi ZhangDepartment of Clinical Laboratory, Xi'an No. 1 Hospital, Xi'an 710000, China.
Yuan SuDepartment of Clinical Laboratory, Xi'an Labor Union Hospital, Xi'an 710000, China.
Davood K HosseiniDepartment of Internal Medicine, Hackensack University Medical Center, Hackensack, NJ 07601, USA.
Han WuDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Minlan YangDepartment of Otorhinolaryngology, Head and Neck Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
Haiying SunDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Huazhong University of Science and Technology · CNUnion Hospital · CNHackensack University Medical Center · USWuhan No.1 Hospital · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence shows that defects in RNA-binding proteins (RBPs) are closely related to the occurrence and development of HNSCC. We obtained 502 tumors and 44 normal samples from the TCGA database, among which 190 differentially expressed RBPs were screened. Finally, a prognostic model containing nine RBPs (

Indexed as

Gene Expression Regulation, NeoplasticAgedBiomarkers, TumorFemaleHead and Neck NeoplasmsHumansMaleMiddle AgedPrognosisRNA-Binding ProteinsSquamous Cell Carcinoma of Head and NeckSurvival RateBiomarkers, TumorRNA-Binding ProteinsHNSCCOSprognostic modelRBPsTCGA database

Identifiers

PMID33758106
PMCPMC8034976
OpenAlexW3136262497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.