Evidence map›Paper›PMID 33758019›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Neural Responses to Heartbeats Detect Residual Signs of Consciousness during Resting State in Postcomatose Patients.

Diego Candia-Rivera, Jitka Annen, Olivia Gosseries, Charlotte Martial, Aurore Thibaut, Steven Laureys, Catherine Tallon-Baudry

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. The Mind From Within: Visceral Roots of Human Cognition.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
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  8. Review
  9. Article
  10. Article
  11. Review
  12. Extracerebral Normalization ofNeurocritical care · 2025
    Article
  13. Cardiac signals inform auditory regularity processing in the absence of consciousness.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Diego Candia-RiveraLaboratoire de Neurosciences Cognitives et Computationnelles, Département d'Etudes Cognitives, École Normale Supérieure, INSERM, Université PSL, 75005 Paris, France diego.candia.r@ug.uchile.cl.ORCID https://orcid.org/0000-0002-4043-217X
Jitka AnnenGIGA-Consciousness, Coma Science Group, University of Liège, 4000 Liège, Belgium.
Olivia GosseriesGIGA-Consciousness, Coma Science Group, University of Liège, 4000 Liège, Belgium.
Charlotte MartialGIGA-Consciousness, Coma Science Group, University of Liège, 4000 Liège, Belgium.
Aurore ThibautGIGA-Consciousness, Coma Science Group, University of Liège, 4000 Liège, Belgium.
Steven LaureysGIGA-Consciousness, Coma Science Group, University of Liège, 4000 Liège, Belgium.
Catherine Tallon-BaudryLaboratoire de Neurosciences Cognitives et Computationnelles, Département d'Etudes Cognitives, École Normale Supérieure, INSERM, Université PSL, 75005 Paris, France.ORCID https://orcid.org/0000-0001-8480-5831
University of Liège · BEInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neural monitoring of visceral inputs might play a role in first-person perspective (i.e., the unified viewpoint of subjective experience). In healthy participants, how the brain responds to heartbeats, measured as the heartbeat-evoked response (HER), correlates with perceptual, bodily, and self-consciousness. Here we show that HERs in resting-state EEG data distinguishes between postcomatose male and female human patients (

Indexed as

Heart RateAdolescentAdultAgedBrainComaElectroencephalographyFemaleHumansMachine LearningMaleMiddle AgedNeurophysiological MonitoringPersistent Vegetative StateSignal Processing, Computer-AssistedYoung Adultcerebral glucose metabolismdisorders of consciousnessheartbeat-evoked responseheart rate variabilityrandom forests

Identifiers

PMID33758019
PMCPMC8211547
OpenAlexW3138479979

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.