Evidence map›Paper›PMID 33757943›Full record

ArticleBMJ open2021

Trends in known and undiagnosed diabetes, HbA1c levels, cardiometabolic risk factors and diabetes treatment target achievement in repeated cross-sectional surveys: the population-based Tromsø Study 1994-2016.

Petja Lyn Langholz, Tom Wilsgaard, Inger Njølstad, Rolf Jorde, Laila Arnesdatter Hopstock

Abstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Type 2 diabetes in Norway 2009-2021: Have declining incidence rates continued?Diabetic medicine : a journal of the British Diabetic Association · 2026
    Article
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  12. Undiagnosed diabetes based on HbABMJ open diabetes research & care · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Petja Lyn LangholzDepartment of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway petja.langholz@uit.no.ORCID http://orcid.org/0000-0001-8225-1345
Tom WilsgaardDepartment of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway.ORCID http://orcid.org/0000-0002-2709-9472
Inger NjølstadDepartment of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway.ORCID http://orcid.org/0000-0002-6391-231X
Rolf JordeDepartment of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway.ORCID http://orcid.org/0000-0002-8803-6408
Laila Arnesdatter HopstockDepartment of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway.ORCID http://orcid.org/0000-0003-0072-7421

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to investigate time trends in known and undiagnosed diabetes, glycated haemoglobin (HbA1c) levels and other cardiometabolic risk factors in the general population as well as treatment target achievement among those with diabetes. DESIGN AND

settingRepeated cross-sectional surveys in the population-based Tromsø Study.

methodsWe used age-adjusted generalised estimating equation models to study trends in self-reported and undiagnosed (HbA1c ≥6.5%) diabetes, cardiometabolic risk factors and the metabolic syndrome in 27 281 women and men aged 40-84 years examined in up to four surveys of the Tromsø Study between 1994 and 2016. Further, we analysed trends in diabetes treatment target achievement.

resultsDuring 1994-2016, diabetes prevalence increased in women (2.3% to 4.6%) and men (2.4% to 5.8%) and in all age groups, while the proportion of undiagnosed diabetes in women (32% to 17%) and men (37% to 24%) decreased. Blood pressure and total cholesterol decreased, while waist circumference increased in participants with and without diabetes, leading to a relatively stable prevalence of the metabolic syndrome throughout the study period. There was a marginal increase in HbA1c levels among participants without diabetes. Only half of those with diabetes achieved the treatment target of HbA1c ≤7.0%.

conclusionIn the last two decades, diabetes prevalence increased, while the proportion of undiagnosed diabetes declined. The prevalence of the metabolic syndrome remained stable throughout, driven by opposing trends with an increase in obesity and a decrease in other cardiometabolic risk factors. HbA1c treatment target achievement did not improve.

Indexed as

Cardiometabolic Risk FactorsDiabetes MellitusAdultAgedAged, 80 and overBlood GlucoseCross-Sectional StudiesFemaleGlycated HemoglobinHumansMaleMiddle AgedPrevalenceRisk FactorsWaist CircumferenceBlood GlucoseGlycated Hemoglobindiabetes & endocrinologyepidemiologygeneral diabetes

Identifiers

PMID33757943
PMCPMC7993331

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.