Evidence map›Paper›PMID 33757709›Full record

ArticleDrug and alcohol dependence2021

"I felt like I had a scarlet letter": Recurring experiences of structural stigma surrounding opioid tapers among patients with chronic, non-cancer pain.

Allyn Benintendi, Sarah Kosakowski, Pooja Lagisetty, Marc Larochelle, Amy S B Bohnert, Angela R Bazzi

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Allyn BenintendiClinical Addiction Research and Evaluation Unit, Section of General Internal Medicine, Boston Medical Center, 801 Massachusetts Avenue, Boston, MA, 02118, USA.
Sarah KosakowskiClinical Addiction Research and Evaluation Unit, Section of General Internal Medicine, Boston Medical Center, 801 Massachusetts Avenue, Boston, MA, 02118, USA.
Pooja LagisettyMichigan Medicine, Department of Internal Medicine, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109, USA; VA Center for Clinical Management Research, 2215 Fuller Road, Ann Arbor, MI, 48105, USA.
Marc LarochelleClinical Addiction Research and Evaluation Unit, Section of General Internal Medicine, Boston Medical Center, 801 Massachusetts Avenue, Boston, MA, 02118, USA.
Amy S B BohnertVA Center for Clinical Management Research, 2215 Fuller Road, Ann Arbor, MI, 48105, USA; Michigan Medicine, Department of Anesthesiology, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109, USA.
Angela R BazziDepartment of Community Health Sciences, Boston University School of Public Health, 801 Massachusetts Avenue, rm 442e, Boston, MA, 02118, USA; Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA. Electronic address: abazzi@health.ucsd.edu.

Funding

A Tailored Behavioral Intervention To Increase Engagement in Opioid Tapering in Primary Care SettingsK23DA047475 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LAGISETTY, POOJA · 2019 to 2023
$970k
Improving urine drug test utility to mitigate prescription opioid riskK23DA042168 · NIDA · BOSTON MEDICAL CENTER · PI LAROCHELLE, MARC · 2017 to 2021
$956k
Preventing HIV infection among people who inject drugs during COVID-19K01DA043412 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BAZZI, ANGELA ROBERTSON · 2017 to 2021
$934k
Heroin use and overdose following changes to individual-level opioid prescribingU01CE002780 · CE · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOHNERT, AMY S B, LAROCHELLE, MARC · 2017 to 2018
$800k
NCIPC CDC HHS U01 CE002780NIDA NIH HHS K01 DA043412NIDA NIH HHS K23 DA042168NIDA NIH HHS K23 DA047475
6 · The paper itself

Abstract

backgroundEfforts to address opioid-involved overdose fatalities have led to widespread implementation of various initiatives to taper (i.e., reduce or discontinue) opioid prescriptions despite a limited understanding of patients' experience.

methodsFrom 2019-2020, we recruited patients with chronic, non-cancer pain who had undergone a reduction in opioid daily dosage of ≥50 % in the past two years at Boston Medical Center or Michigan Medicine. Participants completed semi-structured interviews exploring health history, opioid use, and taper experiences. Inductive analysis, guided by theoretical conceptualizations of structural stigma, identified emergent themes.

resultsAmong 41 participants, three elements of structural stigma were identified across participants' lives. First, participants identified themselves as overlooked subjects of the U.S. opioid crisis, who experienced overprescribing, subsequent stigmatization and surveillance of opioid use (e.g., toxicology screening, "pill counts"), and various tapering initiatives. Second, during the course of pain treatment, participants felt stigmatized and invalidated by cultural norms linking chronic pain to stereotypes of acting disingenuously (e.g., "drug-seeking"). Finally, during and after tapers, institutional policies and programs further increased participants' feelings of marginalization, producing multiple unintended consequences, including reduced access to medical care and feeling "orphaned by the system."

conclusionsOpioid tapers may exacerbate the social production and burden of stigma among patients with chronic pain, especially when processes are perceived to invalidate pain, endorse stereotypes, and label previously effective, acceptable treatment as inappropriate. Findings highlight how various tapering initiatives reinforce the devalued status of people living with chronic pain while also reducing patients' wellbeing and confidence in medical systems.

Indexed as

Chronic PainOpioid-Related DisordersAnalgesics, OpioidEmotionsHumansOpioid EpidemicAnalgesics, OpioidAnalgesicsChronic painOpioidOpioid prescribingPain managementStereotypingStigma

Identifiers

PMID33757709
PMCPMC8058315

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.