ArticleBMC research notes2021
Molecular survey of mcr1 and mcr2 plasmid mediated colistin resistance genes in Escherichia coli isolates of animal origin in Iran.
Article in BMC research notes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- A One Health Perspective onMicroorganisms · 2026Review
- Antimicrobial resistance and characterization of ESBL-producing Escherichia coli from poultry and cattle in Isfahan, Iran.BMC veterinary research · 2025Article
- Understanding Recent Developments in Colistin Resistance: Mechanisms, Clinical Implications, and Future Perspectives.Antibiotics (Basel, Switzerland) · 2025Review
- Mechanisms in colistin-resistant superbugs transmissible from veterinary, livestock and animal food products to humans.Iranian journal of veterinary research · 2025Review
- Exploring the Synergistic Effects of Plant Extracts and Silver Nanoparticles Against Colistin-ResistantAdvanced biomedical research · 2025Article
- Investigation of Antibiotic Resistance ofMicroorganisms · 2024Article
- Mobile Colistin Resistance (Antibiotics (Basel, Switzerland) · 2023Review
- Farm to table: colistin resistance hitchhiking through food.Archives of microbiology · 2023Review
- Prevalence of main quinolones and carbapenems resistance genes in clinical and veterinaryIranian journal of microbiology · 2022Article
- Detection of Colistin Sulfate on Piglet Gastrointestinal Tract Microbiome Alterations.Veterinary sciences · 2022Article
- Screening of colistin-resistant bacteria in livestock animals from France.Veterinary research · 2022Article
- Occurrence ofFrontiers in microbiology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe emergence of colistin-resistant Enterobacteriaceae from human and animal sources is one of the major public health concerns as colistin is the last-resort antibiotic for treating infections caused by multidrug-resistant Gram-negative bacteria. We aimed to determine the prevalence of the prototype widespread colistin resistance genes (mcr-1 and mcr-2) among commensal and pathogenic Escherichia coli strains isolated from food-producing and companion animals in Iran.
resultsA total of 607 E. coli isolates which were previously collected from different animal sources between 2008 and 2016 used to uncover the possible presence of plasmid-mediated colistin resistance genes (mcr-1 and mcr-2) by PCR. Overall, our results could not confirm the presence of any mcr-1 or mcr-2 positive E. coli among the studied isolates. It is concluded that despite the important role of food-producing animals in transferring the antibiotic resistance, they were not the main source for carriage of mcr-1 and mcr-2 in Iran until 2016. This study suggests that the other mcr variants (mcr-3 to mcr-9) might be responsible for conferring colistin resistance in animal isolates in Iran. The possible linkage between pig farming industry and high level of mcr carriage in some countries needs to be clarified in future prospective studies.
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