Evidence map›Paper›PMID 33757411›Full record

ArticleHIV research & clinical practice2021

Ethical and practical considerations for mitigating risks to sexual partners during analytical treatment interruptions in HIV cure-related research.

Karine Dubé, John Kanazawa, Lynda Dee, Jeff Taylor, Danielle M Campbell, Brandon Brown, Mallory O Johnson, Parya Saberi, John A Sauceda, Jeremy Sugarman and 1 more

Open access · greenAbstract read
In one paragraph

Article in HIV research & clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Karine DubéGillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0003-3458-1539
John KanazawaGillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Lynda DeeAIDS Action Baltimore, Baltimore, MD, USA.
Jeff TaylorDelaney AIDS Research Enterprise (DARE) CAB, San Francisco, CA, USA.
Danielle M CampbellDelaney AIDS Research Enterprise (DARE) CAB, San Francisco, CA, USA.
Brandon BrownDepartment of Social Medicine, Population and Public Health, Center for Healthy Communities, University of California, Riverside, Riverside, CA, USA.ORCID 0000-0002-6348-4108
Mallory O JohnsonCenter for AIDS Prevention Studies (CAPS), Division of Prevention Sciences, UCSF, San Francisco, CA, USA.
Parya SaberiCenter for AIDS Prevention Studies (CAPS), Division of Prevention Sciences, UCSF, San Francisco, CA, USA.
John A SaucedaCenter for AIDS Prevention Studies (CAPS), Division of Prevention Sciences, UCSF, San Francisco, CA, USA.
Jeremy SugarmanJohns Hopkins Berman Institute for Bioethics, Baltimore, MD, USA.
Michael J PelusoDivision of HIV, Infectious Diseases and Global Medicine, University of California, San Francisco, CA, USA.
San Francisco AIDS Foundation · USAdvisory Board Company (United States) · USUniversity of North Carolina at Chapel Hill · USAIDS United · USJohns Hopkins Berman Institute of Bioethics · USUniversity of California, Riverside · USUniversity of California, San Francisco · US

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 2001 to 2026
$57.4M
First-in-human study of two anti-SARS CoV-2 antibodies in health volunteersUM1AI126620 · NIAID · WISTAR INSTITUTE · PI MONTANER, LUIS J, RILEY, JAMES L. · 2016 to 2021
$24.5M
Training Program in Substance Use, HIV and Related InfectionsT32DA023356 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Natasha Martin, Steffanie A Strathdee · 2007 to 2026
$7.8M
Training in HIV Translational ResearchT32AI060530 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Diane V Havlir · 2005 to 2026
$6.4M
Training Program for Scientists Conducting Research to Reduce HIV Health DisparitR25MH067127 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Emily A Arnold, Torsten Brian Neilands · 2003 to 2026
$5.4M
Mentoring and Empowerment in the Context of HIV Care for At-Risk PopulationsK24DA037034 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, MALLORY O · 2014 to 2018
$918k
Pilot Integration of Participant-Centered Outcomes in HIV Cure Research in the United States: Implications for Ethical ConductR21MH118120 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DUBE, KARINE · 2019 to 2020
$566k
Perceptions of Risks and Benefits of Participating in HIV Cure-related Research among Diverse Youth and Young Adults Living with HIV in the United StatesR21MH122280 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DUBE, KARINE, SABERI, PARYA · 2020 to 2021
$458k
NIAID NIH HHS T32 AI060530NIAID NIH HHS UM1 AI126620NIDA NIH HHS K24 DA037034NIDA NIH HHS T32 DA023356NIMH NIH HHS P30 MH062246NIMH NIH HHS R21 MH118120NIMH NIH HHS R21 MH122280NIMH NIH HHS R25 MH067127
6 · The paper itself

Abstract

background

objective

methods

results

conclusion

Indexed as

HIV InfectionsSexually Transmitted DiseasesHumansResearch PersonnelSexual PartnersViremiaanalytical treatment interruptionsHIVHIV cure researchpartner protectionpeople living with HIVrisk mitigation

Identifiers

PMID33757411
PMCPMC8272285
OpenAlexW3136100998

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.