ArticleJournal of applied clinical medical physics2021
On the reduction of aperture complexity in kidney SABR.
Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 17 citations in OpenAlex.
- A novel audit methodology to improve detection of planning and delivery errors in passive motion management.Physics and imaging in radiation oncology · 2026Article
- A deep learning approach for predicting linear accelerator output settings in automated radiotherapy planning of oligometastatic cancer.Physics and imaging in radiation oncology · 2026Article
- Implementations of modulation complexity scores and their correlations with treatment plan quality in stereotactic radiation therapy.Medical physics · 2025Article
- Article
- Efficacious patient-specific QA for Vertebra SBRT using a high-resolution detector array SRS MapCHECK: AAPM TG-218 analysis.Journal of applied clinical medical physics · 2024Article
- Characterizing the interplay of treatment parameters and complexity and their impact on performance on an IROC IMRT phantom using machine learning.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundStereotactic ablative body radiotherapy (SABR) of primary kidney cancers is confounded by motion. There is a risk of interplay effect if the dose is delivered using volumetric modulated arc therapy (VMAT) and flattening filter-free (FFF) dose rates due to target and linac motion. This study aims to provide an efficient way to generate plans with minimal aperture complexity.
methodsIn this retrospective study, 62 patients who received kidney SABR were reviewed. For each patient, two plans were created using internal target volume based motion management, on the average intensity projection of a four-dimensional CT. In the first plan, optimization was performed using a knowledge-based planning model based on delivered clinical plans in our institution. In the second plan, the optimization was repeated, with a maximum monitor unit (MU) objective applied in the optimization. Dose-volume, conformity, and complexity metric (with the field edge metric and the modulation complexity score) were compared between the two plans. Results are shown in terms of median (first quartile - third quartile).
resultsSimilar dosimetry was obtained with and without the utilization of an objective on the MU. However, complexity was reduced by using the objective on the MUs (modulation complexity score = 0.55 (0.50-0.61) / 0.33 (0.29-0.36), P-value < 10
conclusionsAperture complexity is reduced in kidney SABR by using an objective on the MU delivery with VMAT and FFF dose rate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.