Evidence map›Paper›PMID 33755916›Full record

ArticleIrish journal of medical science2022

COVID-19 autopsies of Istanbul.

Murat Nihat Arslan, Yalçın Büyük, Nihan Ziyade, Neval Elgörmüş, Gözde Şirin, İsmail Çoban, Muhammed Emin Gökşen, Taner Daş, Arzu Akçay

Open access · bronzeAbstract read
In one paragraph

Article in Irish journal of medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Murat Nihat ArslanIstanbul Morgue Department, Council of Forensic Medicine, Istanbul, Turkey. mnarslan@yahoo.com.ORCID http://orcid.org/0000-0002-9916-5109
Yalçın BüyükCouncil of Forensic Medicine, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-2270-5568
Nihan ZiyadePostmortem Microbiology Laboratory, Istanbul Morgue Department, Council of Forensic Medicine, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-3606-0756
Neval ElgörmüşPostmortem Microbiology Laboratory, Istanbul Morgue Department, Council of Forensic Medicine, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-3472-2020
Gözde ŞirinAutopsy Unit, Istanbul Morgue Department, Council of Forensic Medicine, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-4346-7191
İsmail ÇobanAutopsy Unit, Istanbul Morgue Department, Council of Forensic Medicine, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-8154-180X
Muhammed Emin GökşenAutopsy Unit, Istanbul Morgue Department, Council of Forensic Medicine, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-2073-9190
Taner DaşHistopathology Unit, Istanbul Morgue Department, Council of Forensic Medicine, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-1216-186X
Arzu AkçayPathology Department, Gaziosmanpaşa Hospital Yeniyüzyıl University, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-8343-1153
Istanbul Yeni Yüzyıl University · TRMinistry of Justice · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThe aim of this study is to share autopsy findings of COVID-19-positive cases and autopsy algorithms for safely handling of suspicious bodies during this pandemic.

methodsCOVID-19-positive cases of Istanbul Morgue Department were retrospectively analyzed. Sampling indications for PCR tests in suspicious deaths, macroscopic and microscopic findings obtained in cases with positive PCR tests were evaluated.

resultsIn the morgue department, 345(25.8%) of overall 1336 autopsy cases were tested for COVID-19. PCR test was found positive in 26 cases. Limited autopsy procedure was performed in 7 cases, while the cause of death was determined by external examination in the remaining 19 cases. Male-to-female ratio was found 3.3:1 and mean age was 60.0 ± 13.6 among all PCR-positive cases. Cause of death was determined as viral pneumonia in fully autopsied cases. Most common findings were sticky gelatinous fluid in cavities and firm and swollen lungs, varying degrees of consolidation. In microscopy, diffuse alveolar epithelial damage, type-II pneumocyte hyperplasia, hyaline membrane formation, fibrinous exudate, and fibrinous plaques in the alveoli were the most common findings.

conclusionsIn COVID-19 autopsies, pulmonary findings were found to be prominent and the main pathology was pneumonia. Older age and findings of chronic diseases indicate that the cases were in the multirisk group in terms of COVID-19 mortality.

Indexed as

COVID-19Pneumonia, ViralAgedAutopsyFemaleHumansLungMaleMiddle AgedRetrospective StudiesSARS-CoV-2AutopsyCOVID-19Pulmonary findingsRisk factors

Identifiers

PMID33755916
PMCPMC7985574
OpenAlexW3137269077

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.