Evidence map›Paper›PMID 33755880›Full record

ArticleEndocrine2021

Association between preoperative serum TSH and tumor status in patients with papillary thyroid microcarcinoma.

Aihong Mao, Ning An, Juan Wang, Yuanyuan Wu, Tao Wang, Zhuoying Wang, Haixia Guan, Jun Wang

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Endocrine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Aihong MaoDepartment of Head and Neck Surgery, Gansu Provincial Cancer Hospital, Lanzhou, 730050, China.
Ning AnDepartment of Head and Neck Surgery, Gansu Provincial Cancer Hospital, Lanzhou, 730050, China.
Juan WangDepartment of Head and Neck Surgery, Gansu Provincial Cancer Hospital, Lanzhou, 730050, China.
Yuanyuan WuDepartment of Head and Neck Surgery, Gansu Provincial Cancer Hospital, Lanzhou, 730050, China.
Tao WangDepartment of Head and Neck Surgery, Gansu Provincial Cancer Hospital, Lanzhou, 730050, China.
Zhuoying WangDepartment of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Haixia GuanDepartment of Endocrinology and Metabolism, the First Hospital of China Medical University, Shenyang, 110001, China.
Jun WangDepartment of Head and Neck Surgery, Gansu Provincial Cancer Hospital, Lanzhou, 730050, China. jack3376@126.com.
Gansu Provincial Hospital · CNFirst Hospital of China Medical University · CNFudan University Shanghai Cancer Center · CNGansu Provincial Cancer Hospital Gansu Provincial Academic Instiute for Medical Research · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid-stimulating hormone (TSH) is a growth factor affecting the initiation or progression of papillary thyroid cancer (PTC). However, the relationship between preoperative serum TSH and papillary thyroid microcarcinoma (PTMC) remains controversial. To investigate the relationship between preoperative serum TSH and tumor status of PTMC, a multicentered retrospective study was performed from January 2014 to December 2016. The cohort of this study consisted of 1997 patients who underwent thyroid surgery. Serum TSH concentrations were measured and PTMC was diagnosed based on the post-operation pathological report. Results showed that the preoperative serum TSH concentration was not related to age and gender but was positively associated with tumor size. Furthermore, higher TSH level was associated with extra-thyroidal extension and lymph node metastasis (LNM). These results indicated that TSH might not be involved in the development of PTMC but may be associated with PTMC progression. Preoperative serum TSH concentration should be considered as risk predictor for tumor progression in patients with PTMC.

Indexed as

Carcinoma, PapillaryThyroid NeoplasmsHumansRetrospective StudiesRisk FactorsThyrotropinThyrotropinPapillary Thyroid MicrocarcinomaThyroid-stimulating HormoneTumor progressionTumor size

Identifiers

PMID33755880
OpenAlexW3137714072

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.