ArticleJournal of neuro-oncology2021
Racial/ethnic disparities in treatment pattern and time to treatment for adults with glioblastoma in the US.
Article in Journal of neuro-oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- The Impact of Sociodemographic Disparities on Health-Related Quality of Life for Adults with Gliomas.Cancers · 2026Review
- Gaps in Diagnosis, Treatment, and Outcomes Among Patients with Brain Tumors in the United States: A State-of-the-Art Review.Cancers · 2025Review
- Socioeconomic Factors Associate With Access but not Survival in Neurosurgical Brain Tumor Patients.World neurosurgery · 2025Article
- A Bayesian-driven approach to identify racial inequities in longitudinal care delivery.NPJ digital medicine · 2025Article
- Disparities in clinical trial enrollment related to laser interstitial thermal therapy for central nervous system metastases.Neurosurgical review · 2025Article
- The impact of sociodemographic background on clinical presentation of high-grade gliomas: a multi-institutional retrospective analysis.Journal of neuro-oncology · 2025Article
- Hidden figures underlying quality measures: revealing hidden racial inequalities in end-of-life cancer care delivery: a cohort study.Lancet regional health. Americas · 2025Article
- Enhancing neuro-oncology care through equity-driven applications of artificial intelligence.Neuro-oncology · 2024Review
- Racial/ethnic disparities in all-cause and cause-specific death among children with malignant central nervous system tumours: a registry-based cohort retrospective analysis.EClinicalMedicine · 2024Article
- Challenges and Opportunities in Accessing Surgery for Glioblastoma in Low-Middle Income Countries: A Narrative Review.Cancers · 2024Article
- Sex differences in adverse events in Medicare individuals ≥ 66 years of age post glioblastoma treatment.Journal of neuro-oncology · 2024Article
- High costs, low quality of life, reduced survival, and room for improving treatment: an analysis of burden and unmet needs in glioma.Frontiers in oncology · 2024Review
- Disparities in Neuro-Oncology.Current neurology and neuroscience reports · 2023Review
- Demographic variations and time to initiation of adjunct treatment following surgical resection of anaplastic astrocytoma in the United States: a National Cancer Database analysis.Journal of neuro-oncology · 2023Article
- A population study of clinical trial accrual for women and minorities in neuro-oncology following the NIH Revitalization Act.Neuro-oncology · 2022Article
- Predicting access to postoperative treatment after glioblastoma resection: an analysis of neighborhood-level disadvantage using the Area Deprivation Index (ADI).Journal of neuro-oncology · 2022Article
- Association of Race With Receipt of Proton Beam Therapy for Patients With Newly Diagnosed Cancer in the US, 2004-2018.JAMA network open · 2022Article
- Fifteen-year trends and differences in mortality rates across sex, age, and race/ethnicity in patients with brainstem tumors.Neuro-oncology advancesArticle
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
purposeRace/ethnicity have been previously shown to significantly affect survival after diagnosis with glioblastoma, but the cause of this survival difference is not known. The aim of this study was to examine variation in treatment pattern and time to treatment by race/ethnicity, and the extent to which this affects survival.
methodsData were obtained from the National Cancer Database (NCDB) for adults ≥ 40 with glioblastoma from 2004 to 2016 (N = 68,979). Treatment patterns and time to treatment by race/ethnicity were compared using univariable and multivariable logistic and linear regression models, respectively, and adjusted for known prognostic factors and factors potentially affecting health care access.
resultsBlack non-Hispanics (BNH) and Hispanics were less likely to receive radiation and less likely to receive chemotherapy as compared to White non-Hispanics (WNH). Time to radiation initiation was ~ 2 days longer and time to chemotherapy initiation was ~ 4 days longer in both groups in comparison to WNH.
conclusionBoth race/ethnicity and treatment timing significantly affected survival time, and this association remained after adjustment for known prognostic factors. Additional research is necessary to disentangle the specific causal factors, and the mechanism with which they affect survival.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.