ArticlePloS one2021
Fatality and risk features for prognosis in COVID-19 according to the care approach - a retrospective cohort study.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- A national population-based study of mortality and risk factors in COVID-19-hospitalized patients in Spain (2020-2021).Frontiers in public health · 2025Article
- The nasopharyngeal microbiome in COVID-19.Emerging microbes & infections · 2023Article
- The future of training in intensive care medicine: A European perspective.Journal of intensive medicine · 2023Article
- Association between Clinical Frailty Scale (CFS) and clinical presentation and outcomes in older inpatients with COVID-19.BMC geriatrics · 2023Article
- Septic shock 3.0 criteria application in severe COVID-19 patients: An unattended sepsis population with high mortality risk.World journal of critical care medicine · 2022Article
- Hospitalized patients with breakthrough COVID-19: Clinical features and poor outcome predictors.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022Article
- Nasopharyngeal Microbiota as an early severity biomarker in COVID-19 hospitalised patients.The Journal of infection · 2022Article
- Early carbohydrate antigen 125 as a mortality predictor in hospitalized patients with coronavirus disease 2019.Frontiers in cardiovascular medicine · 2022Article
- Pathological Findings Associated With SARS-CoV-2 on Postmortem Core Biopsies: Correlation With Clinical Presentation and Disease Course.Frontiers in medicine · 2022Article
- Prediction of mortality in COVID-19 through combing CT severity score with NEWS, qSOFA, or peripheral perfusion index.The American journal of emergency medicine · 2021Article
- Palliative Sedation in COVID-19 End-of-Life Care. Retrospective Cohort Study.Medicina (Kaunas, Lithuania) · 2021Article
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14 authors.
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Abstract
introductionThis study analyzed the impact of a categorized approach, based on patients' prognosis, on major outcomes and explanators in patients hospitalized for COVID-19 pneumonia in an academic center in Spain.
methodsRetrospective cohort study (March 3 to May 2, 2020). Patients were categorized according to the followed clinical management, as maximum care or limited therapeutic effort (LTE). Main outcomes were all-cause mortality and need for invasive mechanical ventilation (IMV). Baseline factors associated with outcomes were analyzed by multiple logistic regression, estimating odds ratios (OR; 95%CI).
resultsThirty-hundred and six patients were hospitalized, median age 65.0 years, 57.8% males, 53.3% Charlson index ≥3. The overall all-cause fatality rate was 15.0% (n = 46). Maximum care was provided in 238 (77.8%), IMV was used in 38 patients (16.0%), and 5.5% died. LTE was decided in 68 patients (22.2%), none received IMV and fatality was 48.5%. Independent risk factors of mortality under maximum care were lymphocytes <790/mm3, troponin T >15ng/L and hypotension. Advanced age, lymphocytes <790/mm3 and BNP >240pg/mL independently associated with IMV requirement.
conclusionOverall fatality in the cohort was 15% but markedly varied regarding the decided approach (maximum care versus LTE), translating into nine-fold higher mortality and different risk factors.
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