Evidence map›Paper›PMID 33755322›Full record

ArticleThoracic cancer2021

Diagnosis of miliary nodules as lung adenocarcinoma by cryobiopsy: A case report.

Momoko Morishita, Manabu Suzuki, Hiromu Watanabe, Chie Morita, Akane Ishida, Masao Hashimoto, Go Naka, Yuichiro Takeda, Masayuki Hojo, Haruhito Sugiyama

Open access · goldAbstract readCase Reports
In one paragraph

Article in Thoracic cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Hemoptysis in a 48-Year-Old Man.CHEST pulmonary · 2026
    Article
  2. Examining Miliary Disease Etiology in aJournal of fungi (Basel, Switzerland) · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Momoko MorishitaDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, Japan.ORCID 0000-0002-6357-9465
Manabu SuzukiDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, Japan.ORCID 0000-0001-8515-6466
Hiromu WatanabeDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, Japan.
Chie MoritaDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, Japan.
Akane IshidaDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, Japan.
Masao HashimotoDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, Japan.
Go NakaDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, Japan.
Yuichiro TakedaDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, Japan.
Masayuki HojoDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, Japan.
Haruhito SugiyamaDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, Japan.
National Center for Global Health and Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 62-year-old woman with rheumatoid arthritis and a history of receiving immunosuppressant therapy had a recurrence of lung adenocarcinoma with EGFR L858R mutation. Following 14 months of treatment with erlotinib, computed tomography (CT) findings revealed the presence of small diffuse nodules. Bronchoscopy was performed as metastasis was suspected; however, this was not detected on lung biopsy with forceps. Transbronchial lung cryobiopsy (TBLC) succeeded in detecting metastatic adenocarcinoma, and T790M and L858R gene mutations. Pathological examination revealed a cluster of tumor cells in the intralobular interstitial areas, which was consistent with the CT findings. This report provides important information regarding the role of TBLC in diagnosing metastatic cancer, such as diffuse small miliary nodules, and its genetic mutations.

Indexed as

Adenocarcinoma of LungBiopsyFemaleHumansLung NeoplasmsMiddle AgedEGFR mutationliquid biopsymetastatic lung tumorT790MTBLC

Identifiers

PMID33755322
PMCPMC8107029
OpenAlexW3138918105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.